Genetic determination in endometriosis

Mihaela Țurcan, Ovidiu Maioru, Lucian Pop, Viorica Rădoi, Radu Ursu, Nicolae Bacalbașa, Irina Bălescu, Ioan D. Suciu
In: Romanian Medical Journal · 2022 · vol. 69(S4) , pp. 28–30 · doi:10.37897/rmj.2022.s4.8 · W4283741646
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This paper reviews proposed theories on endometriosis pathogenesis and discusses established and suspected genetic factors contributing to the disease.

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Abstract

Endometriosis represents a debilitating disease affecting women at fertile age which is associated with severe symptoms such as chronic pelvic pain, dysmenorrhea, dyspareunia and infertility. The pathogenesis of this disease is not fully understood so far, multiple theories being proposed. However, more recently, attention was focused on identifying the role of genetic factors in endometriosis development. In the current paper we aimed to review the most important theories regarding pathogenesis. Furthermore we discuss the genetic factors regarding this illness as well as other genes that are suspected to be culprits in leading to this pathology.

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Condition tags

endometriosischronic_pelvic_paindysmenorrheadyspareuniainfertility

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last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK