ITRAQ-based proteomics analysis of tanshinone IIA on human ectopic endometrial stromal cells of adenomyosis

Yong Luo, Zeng-Ming Li, Li-Ping Li, Liping Li, Yang Zou, Xiaoyun Xu, Xiao-Yun Xu, Ziyu Zhang, Zi-Yu Zhang, Faying Liu, Fa-Ying Liu, Yan Xiong, Lei Wan
Archives of gynecology and obstetrics · 2021 · vol. 303(6) , pp. 1501–1511 · doi:10.1007/s00404-020-05936-1 · PMID:33471216 · W3126091725
article OA: closed CC0 ⤵ 4 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-09 ⓘ

Proteomics analysis of tanshinone IIA on human ectopic endometrial stromal cells revealed 267 differential proteins, implicating focal adhesion, ECM-receptor, and estrogen signaling pathways in the drug's inhibitory effects.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Abietanes Cell Proliferation Chromatography, Liquid Female Humans Proteomics Stromal Cells Tandem Mass Spectrometry

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License: CC0 · commercial use OK