Greatly Elevated Serum CA-125 Level in a Patient with a Ruptured Endometrioma

Mark A. Rettenmaier; Bram H. Goldstein; Janet M. Stallman; John V. Brown; John P. Micha

doi:10.1089/gyn.2005.21.117

Greatly Elevated Serum CA-125 Level in a Patient with a Ruptured Endometrioma

Mark A. Rettenmaier, Bram H. Goldstein, Janet M. Stallman, John V. Brown, John P. Micha

In: Journal of Gynecologic Surgery · 2005 · vol. 21(3) , pp. 117–120 · doi:10.1089/gyn.2005.21.117 · W2043488151

article OA: closed CC0 ⤵ 1 in-corpus citation

View on OpenAlex View at publisher

⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

This case report describes a 43-year-old woman who presented with abdominal pain and a greatly elevated CA-125 level of 2275 U/mL, ultimately diagnosed with a ruptured ovarian endometrioma.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Introduction: The clinical relevancy of the serum CA-125 antigen level in assessing gynecologic malignancy has been well established, particularly in ovarian cancer. However, there have been limited case studies reported in the literature of patients with benign disease who have exhibited extremely high CA-125 levels. Case Report: A 43-year-old woman presented with abdominal pain. Her preoperative serum CA-125 level was 2275 U/mL, suggestive of an ovarian malignancy. Surgical findings and histologic evaluation revealed a ruptured ovarian endometrioma. Conclusion: The serum CA-125 marker has often been used to assess malignancy status. Because there are only scant cases of patients with highly elevated CA-125 levels who have exhibited benign findings reported in the literature, gynecologic patients who present with greatly elevated serum CA-125 levels and a pelvic mass should be evaluated for an ovarian malignancy. (J GYNECOL SURG 21:117)

My notes (saved in your browser only)

Condition tags

endometrioma

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

The CA 125 tumour-associated antigen: a review of the literature 1989

Cited by (1)

Relation of high CA125 and CA19-9 levels with recent rupture of endometrioma 2011

References (10)

The CA 125 tumour-associated antigen: a review of the literature via openalex
doi:10.1016/s0301-2115(02)00139-2 via openalex
doi:10.1023/a:1008351216605 via openalex
doi:10.1200/jco.2004.10.028 via openalex
doi:10.1093/humrep/4.suppl_1.1 via openalex
W251362820 via openalex
W2409748313 via openalex
doi:10.1016/s0002-9378(88)80081-4 via openalex
doi:10.1172/jci110380 via openalex
doi:10.1016/j.ygyno.2004.03.003 via openalex

Cited by (1)

Relation of high CA125 and CA19-9 levels with recent rupture of endometrioma 2011

Source provenance

openalex: last seen: 2026-05-11T06:58:05.965230+00:00
unpaywall: last seen: 2026-08-22T06:23:50.750314+00:00

License: CC0 · commercial use OK

[1] The CA 125 tumour-associated antigen: a review of the literature 1989