Post-menopausal endometriosis with inferior vena cava invasion requiring surgical management

R Flyckt, Flyckt R, Rebecca Flyckt, S Lyden, Sean P. Lyden, Andres A. Roma, A Roma, Roma A, Falcone T, T Falcone, Tommaso Falcone
Human Reproduction · 2011 · vol. 26(10) , pp. 2709–2712 · doi:10.1093/humrep/der260 · PMID:21835832 · W2104675344
article OA: bronze CC0 ⤵ 13 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-21 ⓘ

This case report describes a post-menopausal woman with recurrent endometriosis invading the inferior vena cava that necessitated surgical resection despite aromatase inhibitor treatment.

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Abstract

Post-menopausal endometriosis is rare after hysterectomy, and preliminary data support treatment with aromatase inhibitors (AIs). Sites for extrapelvic recurrent disease are wide-ranging; however, no previous case reports have described endometriosis invading the inferior vena cava. A 59-year-old woman status post hysterectomy and bilateral salpingo-oophorectomy for endometriosis developed a periaortic mass with ureteral obstruction. Computerized tomography-guided biopsy confirmed recurrent endometriosis and the lesion enlarged despite treatment with AIs. Vascular surgery, urology and gynecology were involved. The mass was resected surgically and pathology confirmed invasion of the inferior vena cava. Medical management with AIs can be attempted for extra-pelvic endometriosis status post hysterectomy; however, the efficacy in this setting is limited. Surgical management may be necessary for bulky or invasive disease.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Vena Cava, Inferior Biopsy Biopsy Endometriosis Endometriosis Fallopian Tubes Fallopian Tubes Female Humans Hysterectomy Hysterectomy Middle Aged Ovariectomy Ovariectomy Postmenopause Postoperative Complications Tomography, X-Ray Computed Tomography, X-Ray Computed Treatment Outcome

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (17)

Cited by (13)

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