Relation of red cell distribution width to the presence and severity of endometriosis

Raziye Keskin Kurt, R Keskin Kurt, A Citil Dogan, Hüseyin Yeşilyurt, H Yesilyurt, Ateş Karateke, A Karateke, Ayşe Güler Okyay, A Güler Okyay
Clinical and experimental obstetrics & gynecology · 2014 · vol. 41(6) , pp. 713–716 · doi:10.12891/ceog17572014 · PMID:25551970 · W2418193429
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Abstract

AIM: Although the exact pathogenesis of endometriosis is not known, it is proposed to be a chronic inflammatory disease. The asso- ciation between red cell distribution width (RDW) and inflammation is well established. Therefore, in the present study, the authors aimed to investigate the association between presence and severity of endometriosis and RDW. MATERIALS AND METHODS: Fifty endometriosis patients and 48 controls were included in the study. The endometriosis group was categorized in two subgroups as mild-to-moderate (n = 35) and moderate-to-severe disease (n = 15). CA-125 and RDW values of all participants were measured. RESULTS: Both RDW (17.7 ± 2.2 vs 14.9 ± 1.5, p < 0.001) and CA-125 (50.6 ± 35.1 vs 27.9 ± 4.8) levels were significantly higher in the endometriosis patients when compared to the control group. Moreover the authors found a significant positive correlation between RDW and CA-125 levels (r: 0.495, p < 0.001). CONCLUSION: The present study results demonstrated that RDW levels were significantly increased in endometrio- sis patients and associated with the severity of endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Erythrocyte Indices Adult CA-125 Antigen CA-125 Antigen Endometriosis Female Humans Middle Aged

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