The Association Between Endometriosis and an Increased Risk of Epithelial Ovarian Cancer and Cardiovascular Disease: Perspective on a Patient-Centered Approach to Endometriosis, a Heterogeneous Disease

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Abstract

A growing body of literature has revealed that patients with endometriosis are at an increased risk for epithelial ovarian cancer (EOC) and cardiovascular disease (CVD). Endometriosis is a heterogeneous disease in terms of its clinical symptoms and the locations of endometriotic lesions. More epidemiological studies investigating the relationship between endometriosis and the risk of EOC and CVD should incorporate location- and symptom-specific analyses of diverse populations according to geography and ancestry. Such analyses would allow us to more effectively prevent and treat these comorbidities for this heterogeneous disease in a patient-oriented manner and improve our understanding of endometriosis's pathophysiology.

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europepmc
last seen: 2026-07-11T06:07:31.639957+00:00
pubmed
last seen: 2026-07-11T06:02:30.976710+00:00
unpaywall
last seen: 2026-07-09T06:39:34.564547+00:00
License: CC-BY-NC-ND-4.0 · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine