Einfluss von Adenomyose auf plazentavermittelte Schwangerschaftskomplikationen

Herbert Fluhr
In: Gynäkologische Endokrinologie · 2025 · vol. 23(4) , pp. 278–279 · doi:10.1007/s10304-025-00652-y · W4413893436
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This retrospective cohort study investigated women with sonographically diagnosed adenomyosis and found a significantly higher rate of composite abnormal placental function compared to controls.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The paper studied whether sonographically diagnosed adenomyosis is associated with placenta-mediated obstetric complications in a retrospective cohort using data from births after 23 weeks (January 2010 to August 2022) in which adenomyosis was diagnosed within 5 years before or after delivery. After excluding confounders such as uterine malformations, myomas, endometriosis, ART, multiple gestations, and major fetal anomalies, 121 women (59 with adenomyosis and 62 controls) were analyzed, with outcomes including SGA, hypertensive disorders, placental abruption, and postpartum hemorrhage; a composite “abnormal placental function” outcome was also assessed. Women with adenomyosis had a higher composite outcome rate (27% vs 11%), but no statistically significant differences were observed for individual outcomes, including SGA, hypertensive disorders, or postpartum bleeding parameters. The authors attribute the lack of individual-outcome differences to small sample size and strict exclusions plus the retrospective design, and they note that common coexisting pathologies were not addressed, limiting generalizability. This paper is centrally about adenomyosis — it evaluates adenomyosis’ relationship to placenta-mediated pregnancy complications.

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