Localized neurofibromatosis of the female genital system: A case report and review of the literature

Ana María Gómez-Laencina, Francisco Martínez Díaz, Blanca Izquierdo Sanjuanes, Elena Moya Sánchez, Rosario Fernandez Salmerón, Francisco Meseguer Peña
In: Journal of Obstetrics and Gynaecology Research · 2012 · vol. 38(6) , pp. 953–956 · doi:10.1111/j.1447-0756.2011.01816.x · PMID:22487305 · W1571909088
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This case report describes an 11-cm uterine myometrial neurofibroma found in a 71-year-old woman with undiagnosed von Recklinghausen's disease, highlighting neurofibroma as a differential diagnosis for pelvic masses.

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Abstract

Neurofibromatosis within the female genital tract is uncommon. The vulva is the most frequent genital location, but it has rarely been reported in the context of the vagina, uterine cervix or ovaries. In spite of its rarity, neurofibroma is a neoplasm that should be considered in the differential diagnosis of pelvic masses, especially in patients with neurofibromatosis. In this paper we describe the case of a 71-year-old patient with pelvic pain and a uterine mass who underwent a hysterectomy after having been diagnosed with an 11-cm neurofibroma occupying the myometrium of the entire uterine corpus. There were no neurofibromas in the endometrium, serosa, fallopian tubes or ovaries. The patient had an unknown von Recklinghausen's disease.

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