Massive Endometriosis in Two Rhesus Monkeys

J Saegusa, Junzo Saegusa, Yoshikuni Tanioka, Y Tanioka, Hitoshi Koizumi, H Koizumi
Jikken dobutsu. Experimental animals · 1989 · vol. 38(3) , pp. 275–278 · doi:10.1538/expanim1978.38.3_275 · PMID:2792209 · W2402367170
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

Massive endometriosis with metastatic lesions in lymph nodes and intestinal invasion was observed in two rhesus monkeys, suggesting a potentially aggressive behavior similar to neoplasia.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

The paper reports massive endometriosis discovered in two rhesus monkeys during a chronic toxicological experiment. Key observations included endometriotic foci on the serosal wall of pelvic organs, with metastatic-appearing lesions in lymph nodes; in one case there was invasion into the intestinal mucosal layer. The authors interpret these findings as indicating that endometriosis in rhesus monkeys might behave similarly to a malignant neoplasm, while the study is limited to only two observed cases. This paper is centrally about endometriosis — it describes extensive, metastasis-like and mucosal invasion features in rhesus monkeys.

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Abstract

Massive endometriosis was found in two rhesus monkeys during a chronic toxicological experiment. These cases had metastatic lesions in lymph nodes in addition to the foci on the serosal wall of pelvic organs. Invasion to the intestinal mucosal layer was also noted in a case. These observation indicated that endometriosis in the rhesus monkey might behave like a malignant neoplasm.
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Massive Endometriosis in Two Rhesus Monkeys 1989 Volume 38 Issue 3 Pages 275-278 Details Abstract Massive endometriosis was found in two rhesus monkeys during a chronic toxicological experiment. These cases had metastatic lesions in lymph nodes in addition to the foci on the serosal wall of pelvic organs. Invasion to the intestinal mucosal layer was also noted in a case. These observation indicated that endometriosis in the rhesus monkey might behave like a malignant neoplasm. © Japanese Association for Laboratory Animal Science Favorites & Alerts Recently viewed articles

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Intestinal Neoplasms Monkey Diseases Urinary Bladder Neoplasms Animals Endometriosis Endometriosis Intestinal Neoplasms Intestinal Neoplasms Lymphatic Metastasis Macaca mulatta Monkey Diseases Urinary Bladder Neoplasms Urinary Bladder Neoplasms

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