Endometriosis Pathogenesis and Management

Shawky Z.A. Badawy
In: Biomedical Journal of Scientific & Technical Research · 2019 · vol. 19(3) · doi:10.26717/bjstr.2019.19.003299 · W2965140504
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This review discusses the long history of endometriosis, its role as a cause of pain and infertility, and current management strategies.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This mini-review discusses endometriosis pathogenesis and management by synthesizing evidence on proposed mechanisms (e.g., retrograde menstruation, stem cell contributions, genetic predisposition, and uterine “eutopic” endometrium abnormalities marked by altered apoptosis, immune factors, aromatase, growth factors, and invasion/integrin changes). It describes clinical presentations and diagnostic approaches at a high level, including ultrasound staging and laparoscopy with morphologic criteria, and summarizes medical and surgical treatments in broad terms, noting limitations such as the review’s reliance on heterogeneous evidence and that some interventions have reported effects mainly on symptoms rather than lesion size. It also covers extrapelvic manifestations like thoracic and intestinal endometriosis and outlines characteristic diagnostic workups and treatment approaches. This paper is centrally about endometriosis — it focuses on endometriosis pathogenesis, diagnosis, and management, including mechanisms of eutopic endometrium and treatment options.

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Abstract

Endometriosis has been described over 300 years ago [1-3]. It is a major cause of pain and infertilit...

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (14)

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