The fallopian tube and reproductive health
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CC0
⤵ 4 in-corpus citations
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This review discusses the crucial role of the fallopian tube in human reproduction, covering its anatomy, physiology, and involvement in common reproductive pathologies.
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Abstract
The fallopian tube is the essential link between the ovary and the uterus. Its transport mechanisms are now reasonably well understood and include orderly ovum transfer by the fimbria, and ovum/preembryo retention, with transport to the uterus on the third postovulatory day. Sperm/tube interaction ensures a reservoir and storage/activation system at the tubal isthmus. Ovum/tube interaction is driven by the HCO3 ion in the tubal secretions, which also supply pyruvate and other essential substances to the preembryo. Tubal function may be impaired/destroyed by salpingitis, a peritubal disease resulting from ruptured appendix, endometriosis, and ectopic pregnancy (often the result of prior tubal damage with partial occlusion or luminal adhesions). Prophylactic measures include counseling the patient on how to avoid sexually transmitted disease or inhibition of upward ascent of bacteria, and, in the case of ectopic pregnancy, how to use the most efficient contraceptive measures. The least intrusive transfer methods are helpful in avoiding tubal pregnancy following embryo transfer after in vitro fertilization, and results are improved by pretreatment removal of hydrosalpinges. Among adolescents, efforts should be made to preserve tubal function and to increase awareness of the importance of avoiding tubal disease with an eye to preserving future reproductive capacity.
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Cites (4)
- The effect of peritoneal fluid from patients with endometriosis on human sperm function in vitro 1996
- Increased chemotactic activity of peritoneal fluid in patients with endometriosis 1993
- Risk factors for ectopic pregnancy in assisted reproduction 1999
- Angiotensin II receptors and angiotensin II stimulation of ciliary activity in human fallopian tube. 1996
Cited by (2)
- Endometriosis 2009
- Endometriosis 2013
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Cited by (2)
- Endometriosis 2013
- Endometriosis 2009
Source provenance
- europepmc
- last seen: 2026-08-13T06:15:24.848197+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:10:24.024533+00:00
- unpaywall
- last seen: 2026-08-13T06:47:16.638238+00:00
License: CC0
· commercial use OK