LPAR2 and LPAR4 are the Main Receptors Responsible for LPA Actions in Ovarian Endometriotic Cysts

Ilona Kowalczyk-Zieba, Ilona Kowalczyk‐Zieba, Izabela Woclawek-Potocka, Izabela Wocławek-Potocka, Tomasz Wasniewski, Tomasz Waśniewski, Dorota Boruszewska, Katarzyna Grycmacher, Emilia Sinderewicz, Joanna Staszkiewicz‐Chodor, Joanna Staszkiewicz, Slawomir Wolczynski, Sławomir Wołczyński
Reproductive sciences (Thousand Oaks, Calif.) · 2018 · vol. 26(1) , pp. 139–150 · doi:10.1177/1933719118766263 · PMID:29621954 · W2795917702
article OA: closed CC0 ⤵ 5 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-09 ⓘ

Ovarian endometriotic cysts show elevated lysophosphatidic acid synthesis enzymes and overexpression of LPAR2 and LPAR4, which correlate with estrogen and progesterone receptors.

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Condition tags

mesh:D004715

MeSH descriptors

Endometriosis Lysophospholipids Ovarian Cysts Receptors, Lysophosphatidic Acid Receptors, Purinergic P2 Adult Endometriosis Female Humans Lysophospholipase D Lysophospholipids Middle Aged Ovarian Cysts Phospholipases A2 Phospholipases A2 Phosphoric Diester Hydrolases Phosphoric Diester Hydrolases Receptors, Estrogen Receptors, Estrogen Receptors, Lysophosphatidic Acid

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License: CC0 · commercial use OK