O USO DA N-ACETILCISTEÍNA COMO TERAPIA COMPLEMENTAR NO TRATAMENTO DA ENDOMETRIOSE: UMA REVISÃO INTEGRATIVA
This integrative review analyzes evidence on N-acetylcysteine as complementary therapy for endometriosis, finding potential benefits in reducing pain and ovarian endometrioma size despite inconsistent reproductive outcomes.
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This integrative review evaluated the potential of N-acetylcysteine as a complementary therapy for endometriosis by analyzing fifteen articles published between 2021 and 2026. The authors examined scientific evidence regarding the compound's antioxidant and anti-inflammatory properties to determine its impact on pain, ovarian endometrioma size, analgesic use, and fertility outcomes. Results indicated possible benefits in reducing pain and lesion size, alongside promising effects on oxidative stress modulation, although inconsistencies were noted in reproductive outcomes and endometrioma recurrence rates. The study concludes that while N-acetylcysteine shows therapeutic potential, more robust clinical trials are required to establish its efficacy and safety definitively. This paper is centrally about endometriosis — specifically investigating a pharmacological intervention aimed at managing symptoms and disease progression.
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References (16)
- Beyond antioxidant activity, toward redox modulation: N-acetylcysteine (NAC) in endometriosis and uterine leiomyomas via openalex
- Comparing the effect of adjunctive N-acetylcysteine plus low dose contraceptive with low dose contraceptive alone on recurrence of ovarian endometrioma and chronic pelvic pain after conservative laparoscopic surgery: a randomised clinical trial study via openalex
- Dietary supplements for treatment of endometriosis: A review via openalex
- Differential Antioxidant Capacities of Human Endometriotic and Endometrial Cell Models Under H2O2 Exposure via openalex
- Efficacy of N-Acetylcysteine on Endometriosis-Related Pain, Size Reduction of Ovarian Endometriomas, and Fertility Outcomes via openalex
- ENDOMETRIOSE E QUALIDADE DE VIDA: DESAFIOS ATUAIS NO DIAGNÓSTICO E TRATAMENTO via openalex
- N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence via openalex
- N-acetylcysteine stimulates organelle malfunction in endometriotic cells via IFN-gamma signaling via openalex
- Oxidative Imbalance in Endometriosis-Related Infertility-The Therapeutic Role of Antioxidants via openalex
- Targeting inflammation in endometriosis: emerging therapeutic options via openalex
- Targeting Oxidative Stress Involved in Endometriosis and Its Pain via openalex
- The Role of Dietary Supplements in the Treatment of Endometriosis: A Critical Review via openalex
- The Role of Lifestyle and Diet in the Treatment of Endometriosis: A Review via openalex
- W4403738927 via openalex
- W7152747635 via openalex
- W7128433319 via openalex
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- last seen: 2026-11-06T06:06:51.996266+00:00