Recurrent anaphylaxis to a depot form of GnRH analogue

G S Letterie, Letterie GS, D Stevenson, Stevenson D, A Shah, Shah A
Obstetrics and gynecology · 1991 · PMID:1923237
case-report public-domain-us
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This case report describes recurrent anaphylaxis to a depot GnRH analogue, highlighting the need for both acute and chronic management despite the rarity of such severe immediate hypersensitivity reactions.

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Abstract

Experience with depot forms of hormonal preparations suggests that severe adverse reactions are infrequent and immediate hypersensitivity reactions are rare. We report a case of recurrent anaphylaxis to a depot form of GnRH analogue requiring both acute and chronic management.

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Condition tags

endometriosis

MeSH descriptors

Anaphylaxis Leuprolide Adult Anaphylaxis Anaphylaxis Anaphylaxis Delayed-Action Preparations Emergencies Endometriosis Endometriosis Female Humans Leuprolide Skin Tests Time Factors Uterine Neoplasms Uterine Neoplasms

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Source provenance

europepmc
last seen: 2026-09-20T09:27:46.357103+00:00
pubmed
last seen: 2026-05-13T22:11:54.876058+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine