Heterogenous wall thickening of gall blabber: xanthogranulomatous cholecystitis or carcinoma, with type 3 choledochal cyst

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This case report describes a 20-year-old man with xanthogranulomatous cholecystitis and a type 3 choledochal cyst who presented with abdominal pain and fever, highlighting the diagnostic challenge of distinguishing this inflammatory condition from gallbladder carcinoma.

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Abstract

Xanthogranulomatous cholecystitis is an unusual inflammatory disease of the gallbladder characterised by severe proliferative fibrosis and the accumulation of lipid-laden macrophages in areas of destructive inflammation. Its macroscopic appearance may occasionally be confused with gallbladder carcinoma. The authors present a case of xanthogranulomatous cholecystitis with type 3 choledochal cyst in a 20-year-old man who was referred to our hospital with a 1-week history of abdominal pain and fever. He underwent endoscopic sphincterotomy and then open cholecystectomy. A histological diagnosis of xanthogranulomatous cholecystitis was made.

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MeSH descriptors

Carcinoma Cholecystitis Choledochal Cyst Gallbladder Neoplasms Granuloma Xanthomatosis Adult Carcinoma Cholecystitis Cholecystitis Cholecystitis Choledochal Cyst Choledochal Cyst Choledochal Cyst Diagnosis, Differential Gallbladder Neoplasms Gallbladder Neoplasms Granuloma Granuloma Granuloma

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europepmc
last seen: 2026-11-01T09:25:17.647243+00:00
pubmed
last seen: 2026-10-08T21:10:28.861444+00:00
unpaywall
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