[Evaluation of peripheral blood neutrophils activity in women with endometriosis].

Ginekologia polska · 2001 · vol. 72(5) , pp. 431–6 · PMID:11526789 · W2406720804
article OA: closed CC0 ⤵ 3 in-corpus citations
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This study found that women with endometriosis exhibit enhanced reactive oxygen intermediate production and in vivo priming of peripheral blood neutrophils, indicating an ongoing local inflammatory reaction.

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Abstract

Authors evaluated the neutrophils ability of creating reactive oxygen intermediates (ROI) in peripheral blood of 14 patients with endometriosis. These tests were performed using the chemiluminescence method. Enhanced ROI production and in vivo priming phenomenon of neutrophils in endometriosis were reported. The observed increase in oxygen activity of neutrophils was statistically significant only in reaction with the use of fMLP. However performed neutrophils preactivation with TNF-alpha followed by the chemiluminescence test revealed the occurrence of in vivo neutrophil activation in women with endometriosis. Reported data confirm the existence of local inflammatory reaction in the course of endometriosis.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Endometriosis Endometriosis Neutrophils Pelvic Inflammatory Disease Pelvic Inflammatory Disease Adult Endometriosis Female Humans Luminescent Measurements Neutrophils Pelvic Inflammatory Disease

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