Reduction of adhesions with fibrin glue after laparoscopic excision of large ovarian endometriomas

Takeuchi H, Hiroyuki Takeuchi, H Takeuchi, M Awaji, Awaji M, Masanori Awaji, Hashimoto M, Masanori Hashimoto, M Hashimoto, Yoshihiro Nakano, Nakano Y, Y Nakano, Mitsuhashi N, Naoki Mitsuhashi, N Mitsuhashi, Y Kuwabara, Kuwabara Y, Yoshinori Kuwabara
The Journal of the American Association of Gynecologic Laparoscopists · 1996 · vol. 3(4) , pp. 575–579 · doi:10.1016/s1074-3804(96)80033-8 · PMID:9050691 · W2047747962
Other OA: closed CC0 ⤵ 10 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-08 ⓘ

Fibrin glue significantly reduced postoperative adhesions following laparoscopic endometrioma resection, particularly in cases involving larger cysts and pre-existing adhesions.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

STUDY OBJECTIVE: To evaluate the effect of fibrin glue on the formation of adhesions after laparoscopic excision of endometriomas. DESIGN: Prospective case series. SETTING: Department of Obstetrics and Gynecology at a university-affiliated hospital. PATIENTS: Thirty women with ovarian cysts. INTERVENTIONS: In 10 women (16 cysts) we performed laparoscopic resection of endometriomas leaving the ovarian capsule open. Twenty patients (25 cysts) underwent laparoscopic removal of endometriomas and fibrin glue approximation of the ovarian capsule, as well as coating of serosal defects with the glue. At second-look laparoscopy 4 to 6 months after the initial surgery, postoperative adhesion formation was assessed according to the revised American Fertility Society classification. MEASUREMENTS AND MAIN RESULTS: The mean (+/- SEM) adnexal adhesion score in patients without fibrin glue was 8.6 +/- 2.2 at initial surgery and increased slightly to 12.6 +/- 2.6 at second-look laparoscopy. In patients treated with fibrin glue, the score decreased significantly from 10.9 +/- 1.4 to 7.8 +/- 1.3 (p <0.02). The decrease was most marked in women with endometriomas 5 cm or more in diameter and for those with a preoperative adhesion score of 8 or higher. CONCLUSION: Fibrin glue reduced postoperative adhesions after laparoscopic resection of endometriomas.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Endometriosis Fibrin Tissue Adhesive Laparoscopy Ovarian Diseases Endometriosis Endometriosis Female Female Fibrin Tissue Adhesive Fibrin Tissue Adhesive Humans Humans Laparoscopy Laparoscopy Laparoscopy Ovarian Cysts Ovarian Cysts Ovarian Cysts Ovarian Diseases Ovarian Diseases

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (14)

Cited by (10)

Source provenance

europepmc
last seen: 2026-10-11T09:27:45.537177+00:00
openalex
last seen: 2026-05-11T06:09:19.794676+00:00
pubmed
last seen: 2026-10-08T22:00:10.289599+00:00
unpaywall
last seen: 2026-10-16T06:24:35.758740+00:00
License: CC0 · commercial use OK