Tumor-like Lesions, Pathology of the Broad Ligament and Other Uterine Ligaments

In: Encyclopedia of Pathology · 2023 · pp. 625–627 · doi:10.1007/978-3-030-97378-0_5649 · W4390800390
book-chapter OA: closed CC0
Full text JSON View on OpenAlex View at publisher
AI-generated summary by gemini-2.5-flash-lite+body, 2026-07-18

Adrenocortical remnants, appearing as microscopic nodules of adrenal cortical cells in the broad ligament, are an incidental finding that can rarely develop into a functional or nonfunctional adenoma.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Full text 3,426 characters · extracted from oa-doi-fallback · click to expand
Adrenal Rest Synonyms Adrenocortical remnants. Definition Small discrete microscopic nodules of adrenal cortical cells. Clinical Features - Incidence Adrenocortical rest have been identified in 23% of carefully sectioned broad ligaments and collections of Hilus cells are occasionally encountered (Falls 1955). - Site Broad ligament or mesosalpinx. Clinical Presentation They are most commonly an incidental finding (Adashi et al. 1980). - Treatment None. - Outcome Benign accessory tissue (Sasano et al. 1997). Macroscopy Grossly, they appear as small microscopic, yellow nodules, but they may be obscured by fat (Roth et al. 1996). Microscopy Histologically all three cortical layers are recognizable. These remnants may become hypertrophic secondary to adrenal destruction or may, rarely, give rise to a functional or nonfunctional cortical adenoma (Wild et al. 1988). Molecular Features Not clinically relevant. Endometriosis Definition The presence of ectopically located endometrial tissue involving... Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only References and Further Reading Adashi, E. Y., Rosenshein, N. B., Parmley, T. H., & Woodruff, J. D. (1980). Histogenesis of the broad ligament adrenal rest. International Journal of Gynaecology and Obstetrics, 18, 102–104. Falls, J. L. (1955). Accesory adrenal cortex in the broad ligament. Incidence and functional significance. Cancer, 8, 143–150. Goldberg, J. M., Falcone, T., & Diamond, M. P. (2019). Current controversies in tubal disease, endometriosis, and pelvic adhesion. Fertility and Sterility, 112, 417–425. Henderson, D. W., Shilkin, K. B., & Whitaker, D. (1998). Reactive mesothelial hyperplasia vs mesothelioma, including mesothelioma in situ: A brief review. American Journal of Clinical Pathology, 110(3), 397–404. Kobayashi, H., Kawahara, N., Ogawa, K., & Yoshimoto, C. A. (2020). Relationship between endometriosis and obstetric complications. Reproductive Sciences, 27, 771–778. Roth, L. M., Davis, M. M., & Sutton, G. P. (1996). Steroid cell tumor of the broad ligament arising in an accessory ovary. Archives of Pathology & Laboratory Medicine, 120, 405–409. Rowlands, I. J., Nagle, C. M., Spurdle, A. B., & Webb, P. M. (2011). Gynecological conditions and the risk of endometrial cancer. Gynecologic Oncology, 123, 537–541. Sasano, H., Sato, S., Yajima, A., Akama, J., & Nagura, H. (1997). Adrenal rest tumor of the broad ligament: Case report with immunohistochemical study of steroidogenic enzymes. Pathology International, 47, 493–496. Wild, R. A., Albert, R. D., Zaino, R. J., et al. (1988). Virilizing Para-ovarian tumors: A consequence of Nelson’s syndrome? Obstetrics and Gynecology, 71, 1053–1156. Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 2023 Springer Nature Switzerland AG About this entry Cite this entry Alvarado-Cabrero, I. (2023). Tumor-like Lesions, Pathology of the Broad Ligament and Other Uterine Ligaments. In: Stolnicu, S., Ali-Fehmi, R. (eds) Gynecologic Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-97378-0_5649 Download citation DOI: https://doi.org/10.1007/978-3-030-97378-0_5649 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-97377-3 Online ISBN: 978-3-030-97378-0 eBook Packages: MedicineReference Module Medicine

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (2)

References (10)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-08-21T06:37:11.537704+00:00
License: CC0 · commercial use OK