{"paper_id":"025fdbc9-eebf-4c9a-b412-64013ba3dce5","body_text":"Adrenal Rest\nSynonyms\nAdrenocortical remnants.\nDefinition\nSmall discrete microscopic nodules of adrenal cortical cells.\nClinical Features\n-\nIncidence\nAdrenocortical rest have been identified in 23% of carefully sectioned broad ligaments and collections of Hilus cells are occasionally encountered (Falls 1955).\n-\nSite\nBroad ligament or mesosalpinx.\nClinical Presentation\nThey are most commonly an incidental finding (Adashi et al. 1980).\n-\nTreatment\nNone.\n-\nOutcome\nBenign accessory tissue (Sasano et al. 1997).\nMacroscopy\nGrossly, they appear as small microscopic, yellow nodules, but they may be obscured by fat (Roth et al. 1996).\nMicroscopy\nHistologically all three cortical layers are recognizable. These remnants may become hypertrophic secondary to adrenal destruction or may, rarely, give rise to a functional or nonfunctional cortical adenoma (Wild et al. 1988).\nMolecular Features\nNot clinically relevant.\nEndometriosis\nDefinition\nThe presence of ectopically located endometrial tissue involving...\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nReferences and Further Reading\nAdashi, E. Y., Rosenshein, N. B., Parmley, T. H., & Woodruff, J. D. (1980). Histogenesis of the broad ligament adrenal rest. International Journal of Gynaecology and Obstetrics, 18, 102–104.\nFalls, J. L. (1955). Accesory adrenal cortex in the broad ligament. Incidence and functional significance. Cancer, 8, 143–150.\nGoldberg, J. M., Falcone, T., & Diamond, M. P. (2019). Current controversies in tubal disease, endometriosis, and pelvic adhesion. Fertility and Sterility, 112, 417–425.\nHenderson, D. W., Shilkin, K. B., & Whitaker, D. (1998). Reactive mesothelial hyperplasia vs mesothelioma, including mesothelioma in situ: A brief review. American Journal of Clinical Pathology, 110(3), 397–404.\nKobayashi, H., Kawahara, N., Ogawa, K., & Yoshimoto, C. A. (2020). Relationship between endometriosis and obstetric complications. Reproductive Sciences, 27, 771–778.\nRoth, L. M., Davis, M. M., & Sutton, G. P. (1996). Steroid cell tumor of the broad ligament arising in an accessory ovary. Archives of Pathology & Laboratory Medicine, 120, 405–409.\nRowlands, I. J., Nagle, C. M., Spurdle, A. B., & Webb, P. M. (2011). Gynecological conditions and the risk of endometrial cancer. Gynecologic Oncology, 123, 537–541.\nSasano, H., Sato, S., Yajima, A., Akama, J., & Nagura, H. (1997). Adrenal rest tumor of the broad ligament: Case report with immunohistochemical study of steroidogenic enzymes. Pathology International, 47, 493–496.\nWild, R. A., Albert, R. D., Zaino, R. J., et al. (1988). Virilizing Para-ovarian tumors: A consequence of Nelson’s syndrome? Obstetrics and Gynecology, 71, 1053–1156.\nAuthor information\nAuthors and Affiliations\nEditor information\nEditors and Affiliations\nRights and permissions\nCopyright information\n© 2023 Springer Nature Switzerland AG\nAbout this entry\nCite this entry\nAlvarado-Cabrero, I. (2023). Tumor-like Lesions, Pathology of the Broad Ligament and Other Uterine Ligaments. In: Stolnicu, S., Ali-Fehmi, R. (eds) Gynecologic Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-97378-0_5649\nDownload citation\nDOI: https://doi.org/10.1007/978-3-030-97378-0_5649\nPublished:\nPublisher Name: Springer, Cham\nPrint ISBN: 978-3-030-97377-3\nOnline ISBN: 978-3-030-97378-0\neBook Packages: MedicineReference Module Medicine","source_license":"CC0","license_restricted":false}