Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group.

Debra A. Gook; Gook DA; David H. Edgar; Edgar DH

doi:10.1007/s10815-011-9678-6

Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group.

Debra A. Gook, Gook DA, David H. Edgar, Edgar DH

Journal of assisted reproduction and genetics · 2011 · doi:10.1007/s10815-011-9678-6 · PMID:22127676 · PMC3241837

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This study found that slow-cooled human oocytes from young women achieve fertilization and implantation rates comparable to fresh oocytes and cryopreserved embryos, challenging previous reports of reduced clinical efficiency.

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Abstract

Previous reports of slow cooling of human mature oocytes have shown a reduced clinical efficiency relative to fresh oocytes. This study reports that equivalent fertilization and implantation rates to those obtained using fresh oocytes and cryopreserved embryos can be achieved with human mature oocytes dehydrated in 1.5 M propanediol and 0.2 M sucrose at 37°C and cryopreserved using slow cooling rates.

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Cites (1)

Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. 2010

References (52)

Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. via crossref
doi:10.1016/s1472-6483(10)60025-9 via crossref
doi:10.1016/j.fertnstert.2006.07.1546 via crossref
doi:10.1016/s1472-6483(10)60204-0 via crossref
doi:10.1093/humrep/deq146 via crossref
doi:10.1016/s1472-6483(10)60706-7 via crossref
doi:10.1016/j.fertnstert.2007.07.1155 via crossref
doi:10.1016/s1472-6483(10)60766-3 via crossref
doi:10.1016/j.fertnstert.2007.05.050 via crossref
doi:10.1093/humupd/dmm028 via crossref
doi:10.1093/humrep/16.3.411 via crossref
doi:10.1093/humrep/del463 via crossref
doi:10.1093/humrep/den119 via crossref
doi:10.1080/19396360802415778 via crossref
doi:10.1016/s0015-0282(01)02354-8 via crossref
doi:10.1093/humrep/deh442 via crossref
doi:10.1016/s1472-6483(10)60765-1 via crossref
doi:10.1016/j.fertnstert.2009.10.029 via crossref
doi:10.1016/s0015-0282(02)03417-9 via crossref
doi:10.1093/humupd/dmg021 via crossref
doi:10.1002/jcp.1041500123 via crossref
doi:10.1016/0011-2240(92)90022-t via crossref
doi:10.1093/humrep/13.2.376 via crossref
doi:10.1071/rd9950237 via crossref
doi:10.1071/rd06127 via crossref
doi:10.1093/humrep/15.1.175 via crossref
doi:10.1016/j.rbmo.2009.06.002 via crossref
doi:10.1007/s10815-006-9093-6 via crossref
doi:10.1093/humrep/dei346 via crossref
doi:10.1016/j.fertnstert.2006.04.052 via crossref
doi:10.1016/j.fertnstert.2006.04.031 via crossref
doi:10.1016/s1472-6483(10)60764-x via crossref
doi:10.1016/s1472-6483(10)61085-1 via crossref
doi:10.1016/j.fertnstert.2009.01.148 via crossref
doi:10.1016/s1472-6483(10)60171-x via crossref
doi:10.1007/bf01868823 via crossref
doi:10.1016/j.fertnstert.2009.02.067 via crossref
doi:10.1093/oxfordjournals.humrep.a138572 via crossref
doi:10.1016/s1472-6483(10)60093-4 via crossref
doi:10.1016/j.fertnstert.2009.05.088 via crossref
doi:10.1016/j.fertnstert.2009.10.042 via crossref
doi:10.1016/s0015-0282(03)00551-x via crossref
doi:10.1016/j.fertnstert.2008.06.005 via crossref
doi:10.1093/humrep/der008 via crossref
doi:10.1016/j.fertnstert.2011.02.035 via crossref
doi:10.1016/j.rbmo.2009.09.017 via crossref
doi:10.1016/j.fertnstert.2010.01.019 via crossref
doi:10.1016/j.fertnstert.2009.12.065 via crossref
doi:10.1016/j.fertnstert.2010.08.027 via crossref
doi:10.1016/j.fertnstert.2011.05.053 via crossref
doi:10.1007/s10815-009-9382-y via crossref
doi:10.1016/s1472-6483(10)61091-7 via crossref

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[1] Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. 2010