Evaluation of predictive factors for multiple pregnancies during gonadotropin/IUI treatment.

James M. Goldfarb, Goldfarb JM, Peskin B, Barry Peskin, Austin C, Cynthia Austin, Lisbona H, Hanna Lisbona
Journal of assisted reproduction and genetics · 1997 · doi:10.1007/bf02765776 · PMID:9048238 · PMC3454823
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Abstract

PurposeOur purpose was to analyze factors for their predictability of multiple pregnancies in patients treated with a combination of human menopausal gonadotropins (hMG) and intrauterine insemination (IUI).MethodsThe records of all patients conceiving through treatment with hMG/IUI were reviewed for factors predictive of multiple pregnancy.ResultsNinety-one pregnancies reviewed included 78 singleton (86%), 8 twin (9%), and 5 higher-order pregnancies (5%). The total number of follicles > 10 mm was greater in the multiple-pregnancy group and there was a decreased number of postwash sperm in the multiple-pregnancy group. Otherwise there was no significant difference in the factors analyzed.ConclusionsNo factor or combination of factors predicts multiple pregnancies to a degree that it would be helpful in managing or counseling patients.

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