Clinical case reports

Clin Case Rep · ISSN (print) 2050-0904 · 116 papers in corpus
case-report 2025
doi:10.1002/ccr3.70226 ·PMID:39995509

This case report details a 39-year-old woman with a history of endometriosis who presented with severe abdominal pain, vomiting, and nausea, leading to a diagnosis of intestinal perforation caused by endometriosis. The patient underwent eme…

case-report 2025
doi:10.1002/ccr3.70837 ·PMID:40909866

Down syndrome is a risk factor for Hirschsprung's disease. However, the amniotic band sequence does not directly correlate. We present a patient with Down syndrome and associated Hirschsprung's disease, who exhibited findings consistent wit…

case-report 2025
doi:10.1002/ccr3.71036 ·PMID:41031286

Endometrial thickness (ET) is an important parameter of determining endometrial receptivity for in vitro fertilization (IVF) with frozen-thawed embryo transfer (FET). ET is influenced by various intrinsic and extrinsic factors, such as horm…

case-report 2025
doi:10.1002/ccr3.71682 ·PMID:41394934

Abdominal wall endometriosis should be considered in reproductive-aged women presenting with painful anterior abdominal wall masses, particularly following obstetric or gynecological surgery. Histopathology confirming endometrial glands and…

case-report 2025
doi:10.1002/ccr3.70044 ·PMID:39742324

Patients with an unruptured ovarian pregnancy may exhibit signs of shock. Laparoscopy is well-suited for the detection of ovarian pregnancy. Viable pregnancies are possible for patients with ovarian pregnancy and a low risk of ectopic pregn…

other 2025
doi:10.1002/ccr3.70883 ·PMID:40948704

Paradoxical insomnia remains an underdiagnosed condition due to its subjective nature and diagnostic challenges. Clinicians should suspect it in patients with severe sleep complaints but minimal daytime impairment, particularly those resist…

case-report 2025
doi:10.1002/ccr3.71335 ·PMID:41210408

Primary presacral clear cell carcinoma (CCC) of Müllerian origin is extremely rare. Malignant transformation of endometriosis is a known phenomenon, though typically involving the ovaries or pelvic peritoneum. Retroperitoneal presentation, …

case-report 2025
doi:10.1002/ccr3.71412 ·PMID:41268295

We report a 67-year-old female diagnosed with ovarian mesonephric-like adenocarcinoma (MLA) and treated with a comprehensive regimen. This case emphasizes the urgent need for standardized diagnostic criteria and evidence-based treatment pro…

case-report 2025
doi:10.1002/ccr3.70929 ·PMID:41909092

Patients with deep endometriosis of the posterior pelvic compartment might present various lower urinary tract symptoms, including urinary retention, without any prior pelvic surgery in their medical history. These symptoms, including urina…

other 2025
doi:10.1002/ccr3.70705 ·PMID:41200460

Sister Mary Joseph's nodule represents a rare sign of advanced abdominal or pelvic malignancy, which indicates a poor prognosis for the patient. All clinicians should be aware of its significance and urgently refer the patient for further i…

case-report 2025
doi:10.1002/ccr3.71337 ·PMID:41142219

Umbilical cutaneous metastases of abdomino-pelvic tumors are rare. They are known as Sister Mary Joseph nodules. The presence of this nodule indicates an advanced cancerous lesion and is associated with a poor prognosis. Because of its rari…

case-report 2025
doi:10.1002/ccr3.71366 ·PMID:41158813

Spontaneous hemoperitoneum is a rare yet potentially life-threatening condition characterized by the accumulation of blood in the peritoneal cavity without a traumatic cause. It is rare for a uterine leiomyoma to present with a massive hemo…

other 2025
doi:10.1002/ccr3.70813 ·PMID:40843104

Acute pancreatitis is inflammation of the pancreas and is most commonly caused by gallstones, alcohol use, hyperlipidemia, or idiopathic. Drug-induced acute pancreatitis is relatively rare and often under-recognized; it accounts for 0.1%-2%…

case-report 2024
doi:10.1002/ccr3.8384 ·PMID:38223515

KEY CLINICAL MESSAGE: In this case, a patient experienced rare uterine torsion during pregnancy, detected by MRI. Diagnosis before Cesarean is helpful to achieve better outcomes, highlighting the importance of attention in high-risk groups.…

case-report 2024
doi:10.1002/ccr3.8766 ·PMID:38595964

KEY CLINICAL MESSAGE: Secondary hematocolpos is a rare but serious complication after cystocele repair. This warrants multidisciplinary management (gynecology and urology) to optimize outcomes & minimize iatrogenic risks. ABSTRACT: Hematoc…

case-report 2024
doi:10.1002/ccr3.8413 ·PMID:38188844

KEY CLINICAL MESSAGE: Cavernous hemangiomas are rare and have various non-specific clinical presentations, such as menorrhagia. It can mimic different diseases such as endometrial polyps. Pathologists and gynecologists should be aware of pe…

case-report 2024
doi:10.1002/ccr3.9708 ·PMID:39649515

Cornual pregnancy, a rare and life-threatening form of ectopic pregnancy, poses significant diagnostic and therapeutic challenges due to its deep implantation in the uterus. This report presents a case of a 31-year-old woman with a history …

case-report 2024
doi:10.1002/ccr3.8925 ·PMID:38808197

KEY CLINICAL MESSAGE: Colorectal cancer is the third most common malignancy worldwide, with an increasing incidence. Colonic metastasis is a rare occurrence; thus, misdiagnosis is common. Immunohistochemistry facilitates accurate diagnosis …

other 2024
doi:10.1002/ccr3.70003 ·PMID:39687657

Timely diagnosis and surgical intervention are crucial in managing hydrocele of the canal of Nuck. A systematic approach, including thorough examination and appropriate imaging, followed by meticulous surgical technique, ensures successful …

case-report 2024
doi:10.1002/ccr3.8859 ·PMID:38725929

While adenomyosis is commonly associated with a mild risk of thrombotic complications, the presence of additional thrombophilia factors can increase this risk, particularly in individuals with severe symptoms and elevated CA125 levels.

case-report 2024
doi:10.1002/ccr3.70009 ·PMID:39687662

Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a rare congenital disorder characterized by agenesis of the uterus and upper two-thirds of the vagina. It affects around 1 in 4000-5000 females and is of two types: type 1, also known as is…

case-report 2024
doi:10.1002/ccr3.8604 ·PMID:38449895

Although endometriosis is a common condition, both extrapelvic endometriosis and endometriosis associated malignancy (EAM) are rare. We describe the first reported case of a patient with Müllerian-type carcinosarcoma arising in gastric endo…

2024
2024
case-report 2024
doi:10.1002/ccr3.9343 ·PMID:39210927

Polypoid endometriosis is a rare manifestation of endometriosis, which may mimic pelvic cancer. This subtype commonly encountered in post-menopausal women may be wrongly mistaken for a neoplasm on clinical, radiological, perioperative or pa…