Frontiers in reproductive health

A 30-year-old woman with a body mass index of 20.6 kg/m² consulted due to two years of primary infertility. The patient had a history of two unsuccessful previous rounds of ovarian stimulation for IVF due to poor ovarian response. A novel o…

BACKGROUND: Although azithromycin has demonstrated potential therapeutic efficacy in the treatment of chronic endometritis (CE), comprehensive studies on the optimal timing of administration are lacking. Our study aims to evaluate the impac…

BACKGROUND: Endometriosis is a benign and chronic gynecological estrogen-dependent disease. Research has shown that endometriosis can affect various dimensions of women's lives. It is recommended that programs be developed to improve the qu…

INTRODUCTION: Frozen embryo transfer (FET) is a standard procedure that improves live birth rates and reduces ovarian hyperstimulation risks. Optimizing luteal phase support with hormone replacement therapy (HRT), particularly by progestero…

BACKGROUND: Infertility is a real public health problem today with clinical and psychological aspects. OBJECTIVE: To improve the care and monitoring of women with primary infertility at the Angré University Hospital Center. MATERIALS AND …

Endometriomas are a common manifestation of endometriosis in women of reproductive age and pose a clinical challenge due to their association with pain, infertility, and compromised ovarian reserve. Surgical removal through cystectomy remai…

PURPOSE: Alström syndrome (AS) is an extremely rare, autosomal recessive genetic disorder. Fertility implications are particularly relevant for women affected by AS, and no cases of patients achieving pregnancy and live birth with in vitro …

Hormonal contraceptives (HCs) are commonly prescribed medications that have had immeasurable impacts on quality of life and health of women and families globally. However, usage of exogenous hormones is not without risks, and patients often…

Polycystic ovary syndrome (PCOS) is a major factor in female infertility. The global burden of PCOS has generally been neglected due to insufficient data. This study aims to comprehensively assess the burden of PCOS among females aged 10-54…

BACKGROUND: Endocrine-disrupting chemicals (EDCs) disrupt hormonal regulation and pose health risks. Phthalates, common in personal care products, contribute to disparate chemical exposures among different demographic groups, notably impact…

INTRODUCTION: Although advanced paternal age (APA) is increasingly scrutinized in reproductive medicine, its independent impact on embryo development and clinical outcomes remains contentious, particularly when controlling for maternal age …

IntroductionTubal factor infertility is one of the most prevalent and diagnostically complex causes of female infertility. Standard imaging modalities, including hysterosalpingography and laparoscopy, frequently fail to detect subtle mucosa…

BACKGROUND: Abnormal uterine bleeding (AUB) is a common reason for women to seek healthcare, affecting their health, quality of life, productivity, and increasing the risk of complications. While menstrual disorders have been studied in Eth…

BACKGROUND: Endometriosis affects approximately 10% of women of reproductive age; this prevalence may be underestimated, mostly in developing countries, including Mexican and Hispanic populations, due to socioeconomic barriers and limited a…

INTRODUCTION: Assisted reproductive technologies (ART) are widely used to address infertility; however, they are costly, associated with medical risks, and often yield suboptimal clinical outcomes. Natural Procreative Technology, also known…

BACKGROUND: Infertility is an underrecognized disease which affects over 17% of the reproductive age population worldwide. However, availability of, and access to, assisted reproductive technology (ART) is variable across countries. There a…

OBJECTIVE: To evaluate the predictive value of hematologic inflammatory indices derived from complete blood count (CBC) parameters for in vitro fertilization (IVF) outcomes in women with unexplained infertility, and to determine their poten…

PURPOSE: To evaluate the effectiveness and safety of the novel protocol-progestin-primed ovarian stimulation (PPOS) protocol during controlled ovarian hyperstimulation (COH), in patients undergoing in vitro fertilization/intracytopalsmic sp…

Adenomyosis, an estrogen-dependent disorder, requires long-term therapy as current treatments (GnRH agonists, danazol, etc.) show symptom recurrence post-discontinuation. Dienogest (DNG), a selective progesterone receptor agonist, effective…

The impact of endocrine-disrupting chemicals (EDCs) on public health is growing due to their wide-ranging consequence and likelihood of morbidity on human health. Humans are confronted with EDCs through their skin and drinks, as well as by …

BACKGROUND: Aberrant vascular endothelial growth factor (VEGF)-driven angiogenesis is central to the establishment and persistence of endometriosis. Although numerous anti-angiogenic compounds have been tested, evidence remains fragmented, …

OBJECTIVE: To analyze the effect of autologous platelet-rich plasma (PRP) intrauterine perfusion on the clinical outcomes of frozen-thawed embryo transfer in patients with chronic endometritis. METHODS: A retrospective continuous cohort of…

INTRODUCTION: The trend of older pregnant women and infertile women in South Korea, who are influencing the low birth rate, is on the rise. Older infertile women earnestly hoped for pregnancy and persisted in undergoing assisted reproductiv…

OBJECTIVE: Endometriosis is a gynecological disorder for which awareness and detection rates are rising globally. The purpose of this study is to highlight atypical presentations of the disease; to present four adolescent patients with lapa…

This Perspectives article reflects on findings from our systematic review about adolescent dysmenorrhoea Q, drawing on sociology of diagnosis theory. We consider tensions and uncertainties between presentation with symptoms of dysmenorrhoea…