Current opinion in pharmacology

Curr Opin Pharmacol · ISSN (e) 1471-4973 · 4 papers in corpus
review 2022
doi:10.1016/j.coph.2022.102311 ·PMID:36279764

In the past, the primary approach for the treatment of endometriosis was represented by surgery; however, after the introduction of non-invasive diagnosis of endometriosis with the development of imaging technologies, medical treatment beca…

2022
doi:10.1016/j.coph.2022.102274 ·PMID:35994915

Pituitary gonadotrophs play a key role in reproductive functions by secreting luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The LH secretory activity of gonadotroph is controlled by hypothalamic gonadotropin-releasing hor…

2011
doi:10.1016/j.coph.2011.03.010 ·PMID:21511531

The large FK506-binding protein FKBP52 has been characterized as an important positive regulator of androgen, glucocorticoid and progesterone receptor signaling pathways. FKBP52 associates with receptor-Hsp90 complexes and is proposed to ha…

2010
doi:10.1016/j.coph.2010.09.009 ·PMID:20951642

Estrogenic effects are mediated through two estrogen receptor (ER) subtypes, ERα and ERβ. Estrogens are the most commonly prescribed drugs to treat menopausal conditions, but by non-selectively triggering both ERα and ERβ pathways in differ…