Annals of translational medicine

Ann Transl Med · ISSN (print) 2305-5839 · 96 papers in corpus
other 2020
doi:10.21037/atm-20-2070 ·PMID:32953713
review 2020
doi:10.21037/atm-20-2449 ·PMID:33490227

Endometriosis is a gynecological disorder that affects 176 million women worldwide and 1 in 10 females in the United States. Endometriosis most often affects women of child-bearing age, with most going undiagnosed. Endometriosis also shares…

review 2020
doi:10.21037/atm-20-3022a ·PMID:33490224

Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of reproductive age. It is defined by the presence of endometrial-like tissue in localizations outside of the uterine cavity. It often causes symptoms such…

other 2020
doi:10.21037/atm-20-2180 ·PMID:33313103

BACKGROUND: Low-grade endometrial stromal sarcoma (LGESS) is the second most common malignant mesenchymal tumor of the uterus which usually affects young women. However, the researches on the safety and feasibility of the fertility-sparing …

other 2020
doi:10.21037/atm-2020-118 ·PMID:33209866
lab-animal 2020
doi:10.21037/atm.2019.12.08 ·PMID:32175347

BACKGROUND: This study aims at investigating the effect of growth hormone (GH) on the growth of human endometrial glandular cells (hEGCs) and preliminary exploring its mechanism. METHODS: HEGCs were isolated from the endometrial biopsies a…

other 2020
doi:10.21037/atm.2020.02.15 ·PMID:32355821

BACKGROUND: This study investigated the effects of medroxyprogesterone acetate (MPA) on the oocytes and embryos in patients with advanced endometriosis who had a normal ovarian reserve and tubal infertility and received controlled ovarian h…

lab-animal 2020
doi:10.21037/atm-20-4915 ·PMID:32793720

BACKGROUND: Hypoxia following ischemic stroke is a common cause of brain insults. Mounting evidence suggests that long non-coding RNAs (lncRNAs) play a vital role in regulating certain physiological and pathological processes including isch…

other 2020
doi:10.21037/atm-20-7296 ·PMID:33490157

BACKGROUND: We aim to assess the long-term efficacy of transvaginal high uterosacral ligament suspension (HUS) procedure for middle compartment defect-based pelvic organ prolapse (POP). METHODS: We performed a retrospective review of 84 wo…

other 2020
doi:10.21037/atm-2020-98 ·PMID:33313279
observational 2020
doi:10.21037/atm-20-1309 ·PMID:33313185

BACKGROUND: Endometriosis is a benign, chronic, gynecological disease which affect the women in reproductive age. The dysfunction of immune system is associated with endometriosis and the diversity of microbiota in genital tract. According …

other 2020
doi:10.21037/atm-2020-oc-14 ·PMID:33490214
lab-animal 2020
doi:10.21037/atm-20-6810 ·PMID:33313249

BACKGROUND: Studies have considered long non-coding RNA 5 prime to Xist (lncRNA FTX) a key lncRNA for normal uterine development, but it has not been reported whether lncRNA FTX is involved in regulating the development of endometriosis (EM…

observational 2020
doi:10.21037/atm-20-1459 ·PMID:33437789

BACKGROUND: Peak endometrial thickness (EMT), measured on the end of follicular phase or early luteal phase, is the most widely used marker for endometrial receptivity during infertility treatment. However, the clinical significance of foll…

observational 2020
doi:10.21037/atm.2019.11.124 ·PMID:32175346

BACKGROUND: Intrauterine adhesion (IUA) is one of the most important causes of female infertility, while iatrogenic endometrial injury is the main, but not the entire, cause of IUA. The microorganisms of the female reproductive tract play a…

other 2020
doi:10.21037/atm.2020.03.36 ·PMID:32395464
other 2020
doi:10.21037/atm.2019.12.109 ·PMID:32175392

BACKGROUND: This study aimed to explore whether intrauterine infusion of peripheral blood mononuclear cells (PBMCs) could induce favorable transcriptomic changes in the endometrium for embryo implantation and the potential mechanism. METHO…

other 2020
doi:10.21037/atm.2020.04.18 ·PMID:32793691
observational 2019
doi:10.21037/atm.2019.04.78 ·PMID:31317012

BACKGROUND: Fibrinogen concentrations and the monocyte-to-lymphocyte ratio (FC-MLR) are associated with progression and outcomes of many malignancies. This study aimed to assess the clinical and prognostic significance of the combination of…

rct 2019
doi:10.21037/atm.2019.04.16 ·PMID:31157267

BACKGROUND: This clinical trial aimed to compare the clinical efficacy of highly purified human menopausal gonadotropin (HP-HMG) plus recombinant human follicle-stimulating hormone (rFSH) versus rFSH alone on controlled ovarian stimulation …

review 2019
doi:10.21037/atm.2019.12.119 ·PMID:32016099

Endometriosis is a gynecological disease that affects 1 in 10 women worldwide and is characterized by the presence of lesions made up of endometrial cells (ECs) outside of the uterus. Symptoms associated with endometriosis include pain and …

other 2019
doi:10.21037/atm.2019.09.30 ·PMID:32047768

BACKGROUND: Accurate preoperative pathologic diagnosis is very important for making appropriate therapeutic decisions for patients with rectal lesions. This study aimed (I) to determine diagnostic value and safety of endoscopic forceps biop…

other 2019
doi:10.21037/atm.2019.11.58 ·PMID:32042787

BACKGROUND: The effects of letrozole plus human menopausal gonadotropin (HMG) on ovarian stimulation (OS) of intrauterine insemination (IUI) cycles were examined. METHODS: In all, 1,005 IUI cycles were included in this study. Couples under…

lab-animal 2019
doi:10.21037/atm.2019.11.73 ·PMID:32042783

BACKGROUND: Endometriosis (EM) is a common gynecological disease in women of reproductive age. These patients in approximately 80% suffer the various degree pain. This study will investigate synergistically the mechanism of the higher-posit…

lab-animal 2019
doi:10.21037/atm.2019.10.76 ·PMID:31930064

BACKGROUND: Endometriosis is a benign gynecological disorder which shares certain characteristics with malignant tumor like migration, invasion and proliferation. Glioma-associated oncogene homolog 1 (GLI1) has been implicated in some cance…