Functional magnetic resonance imaging evaluation of central sensitization in an experimental model of pain in rats with induced endometriosis

Rosa-E-Silva JC, Julio Cesar Rosa-E-Silva, Júlio César Rosa e Silva, Herren H, H Herren, Helmer Herren, Meola J, Juliana Meola, Omero Benedicto Poli‐Neto, Omero Benedicto Poli-Neto, Poli-Neto OB, Ana Carolina Japur de Sá Rosa e Silva, Ana Carolina Japur de Sá Rosa-E-Silva, Rosa-E-Silva ACJS
Annals of translational medicine · 2020 · vol. 8(20) , pp. 1286 · doi:10.21037/atm-2020-118 · PMID:33209866 · PMC7661871 · W3080673005
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⚙ AI-generated summary by claude@2026-07+body, 2026-07-04 ⓘ

This study utilized functional magnetic resonance imaging to evaluate central sensitization in an experimental rat model of induced endometriosis.

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The paper used an experimental rat model with induced endometriosis to evaluate central sensitization of pain using functional magnetic resonance imaging (fMRI). The study measured brain activity patterns associated with pain processing during the induced pain state, aiming to identify functional signatures consistent with central sensitization. A key limitation is that the article does not provide the full methodological and results details in the supplied text and also notes it was commissioned and did not undergo external peer review. This paper is centrally about endometriosis — it uses induced endometriosis in rats to assess central sensitization via fMRI.

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Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

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Provenance and Peer Review: This article was commissioned by the editorial office, Annals of Translational Medicine . The article did not undergo external peer review. Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm-2020-118 ). The authors have no conflicts of interest to declare.

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endometriosis

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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