Biotechnology letters

2022

Stem cells or their exosomes: which is preferred in COVID-19 treatment?

doi:10.1007/s10529-021-03209-8 ·PMID:35043287

It only took 8 months for the pneumonia caused by a previously unknown coronavirus to turn into a global pandemic of unprecedentedly far-reaching implications. Failure of the already discovered treatment measures opened up a new opportunity…

2018

Sublethal concentration of H2O2 enhances the protective effect of mesenchymal stem cells in rat model of spinal cord injury.

doi:10.1007/s10529-017-2499-7 ·PMID:29288352

ObjectiveTo investigate the effect of H2O2 on the migration and antioxidant defense of mesenchymal stem cells (MSCs) and the neurotrophic effects of H2O2-treated MSCs on spinal cord injury (SCI).ResultsSublethal concentrations of H2O2 decre…

2017

All-trans retinoic acid enhances in vitro mesenchymal stem cells migration by targeting matrix metalloproteinases 2 and 9.

doi:10.1007/s10529-017-2350-1 ·PMID:28488074

ObjectivesTo investigate the effect of all-trans retinoic acid (ATRA) on caspase 3 activity, matrix metalloproteinase 2 (MMP-2), and MMP-9 expression and activity as well as in vitro rat bone marrow-derived mesenchymal stem cells (MSCs) mig…

2017

Promigratory and proangiogenic effects of AdipoRon on bone marrow-derived mesenchymal stem cells: an in vitro study.

doi:10.1007/s10529-016-2214-0 ·PMID:27627895

ObjectivesTo investigate the effect of AdipoRon on major factors involved in survival, migration and neovascularization of rat bone marrow-derived mesenchymal stem cells.ResultsAdipoRon promoted the MSCs viability. Real-time PCR indicated t…