Analytical biochemistry

article 2026

FTIR spectroscopy combined with machine learning reveals molecular signatures distinguishing three phenotypes of endometriosis

doi:10.1016/j.ab.2026.116047 ·PMID:41500442

Endometriosis is a chronic inflammatory disorder in which endometrial tissue grows outside the uterus, leading to pelvic pain and infertility. It remains a major challenge in women's health due to delayed diagnosis and limited therapeutic o…

other 2013

Enhancement of ovarian tumor classification by improved reproducibility in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of serum glycans

doi:10.1016/j.ab.2013.07.048 ·PMID:23969014

The serum N-glycome is a promising source of biomarker discovery. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) profiling of serum N-glycans was attempted for differentiating borderline ovaria…

2009

High-quality genomic DNA extraction from formalin-fixed and paraffin-embedded samples deparaffinized using mineral oil.

doi:10.1016/j.ab.2009.08.016 ·PMID:19698695

Extracting DNA from formalin-fixed and paraffin-embedded (FFPE) tissue remains a challenge, despite numerous attempts to develop a more effective method. Polymerase chain reaction (PCR) success rates with DNA extracted using current methods…