Reproductive sciences (Thousand Oaks, Calif.)

Reprod Sci · ISSN (e) 1933-7205 · 747 papers in corpus
lab-animal 2025
doi:10.1007/s43032-025-01823-9 ·PMID:40113654

Endometriosis is a common gynecological disease that causes severe pain and infertility. However, the available treatments for EMS are limited. SCM-198, a synthetic form of leonurine, possesses various abilities, including anti-inflammatory…

observational 2025
doi:10.1007/s43032-025-01802-0 ·PMID:39915377

Endometrial polyps are hyperplastic overgrowths of the endometrium that contain both glands and stroma. Myoma uteri is the most common benign tumor of the female pelvis and uterus. HOXA10, which is involved during the organogenesis of the u…

meta-analysis 2025
doi:10.1007/s43032-025-01940-5 ·PMID:40768027

A systematic review was conducted pertaining to the biologic processes of cumulus cells and measures of oocyte quality. The initial search yielded 18,549 articles, and after screening, 65 studies were included in this review. Extracted data…

other 2025
doi:10.1007/s43032-025-01893-9 ·PMID:40474053

Uterine fibroids, or leiomyomas, are noncancerous tumors of the myometrium and the most common tumors in women, with a cumulative incidence of approximately 80% by age 50. Currently, hysterectomy is the only definitive cure, and effective n…

review 2025
doi:10.1007/s43032-025-01999-0 ·PMID:41145947

Endometriosis is a prevalent chronic inflammatory condition impacting 5-10% of reproductive-age women, commonly resulting in debilitating pelvic pain and infertility. Despite extensive research efforts, the precise underlying pathophysiolog…

review 2025
doi:10.1007/s43032-025-01985-6 ·PMID:41082090

Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus, leading to pain and infertility. Recent research has highlighted the important role of the microbiome in various h…

review 2025
doi:10.1007/s43032-025-01934-3 ·PMID:40676401

Cervical endometriosis is an uncommon site and a distinctive entity of this enigmatic disease. It has a different clinical presentation, more difficult diagnosis and dissimilar management approach. Endometriosis of the cervix can be classif…

lab-animal 2024
doi:10.1007/s43032-023-01426-2 ·PMID:38180609

This study is aimed at identifying variations in the effect of endometriosis on fecundity in a mouse model based on prior pregnancy experience. Endometriosis is one of the most prevalent gynecological diseases and is known to impact female …

lab-animal 2024
doi:10.1007/s43032-024-01458-2 ·PMID:38294669

Thin endometrium (TE), which mainly occurs as a result of severe damage to the endometrial basalis, is one of the prominent etiologies of menstrual abnormalities, infertility, and recurrent miscarriage in women. Previous studies have demons…

review 2024
doi:10.1007/s43032-024-01585-w ·PMID:38740655

The highest frequency of genetic alterations in the tumor suppressor ARID1A occurs in malignancies of the female reproductive tract. The prevalence of ARID1A alterations in gynecologic precancers and cancers is summarized from the literatur…

observational 2024
doi:10.1007/s43032-024-01584-x ·PMID:38767768

The utilization of donor eggs has broadened the options for Assisted Reproductive Technology (ART) among women facing challenges with egg quantity or quality. Given that donors are typically selected from young and fertile individuals, In V…

meta-analysis 2024
doi:10.1007/s43032-024-01587-8 ·PMID:38720155

Adenomyosis is associated with dysmenorrhea and chronic pelvic pain; however, the triggering mechanisms of painful stimuli and the role of uterine nerve fibers in the manifestation of pain remain poorly understood. The objective of this stu…

meta-analysis 2024
doi:10.1007/s43032-024-01515-w ·PMID:38512699

While endometriosis is a common gynecologic disease associated with infertility, the psychosocial impact of endometriosis has not been evaluated against various quality of life (QoL) instruments and compared with other chronic illnesses. We…

lab-animal 2024
doi:10.1007/s43032-024-01592-x ·PMID:38767769

Endometriosis (EM) is a common gynecologic condition that often leads to infertility in women of reproductive age. Cell adhesion molecule 2 (CADM2) is involved in maintaining cell adhesion and polarity, as well as suppressing tumors. Howeve…

observational 2024
doi:10.1007/s43032-024-01628-2 ·PMID:38907127

PURPOSE: To describe the clinical and imaging characteristics of Herlyn-Werner-Wunderlich syndrome (HWWS). METHODS: This study presented an observational case series involving consecutive patients diagnosed with HWWS, whose medical records…

meta-analysis 2024
doi:10.1007/s43032-024-01671-z ·PMID:39168919

ICSI may face fertilization failure, prompting the use of assisted oocyte activation (AOA) techniques. While AOA is implemented in infertility clinics, its target patients and definitive application remain uncertain. This systematic review …

other 2024
doi:10.1007/s43032-024-01609-5 ·PMID:38819523
other 2024
doi:10.1007/s43032-024-01556-1 ·PMID:38649668
other 2024
doi:10.1007/s43032-024-01528-5 ·PMID:38570438
other 2024
doi:10.1007/s43032-024-01466-2 ·PMID:38267809
other 2024
doi:10.1007/s43032-024-01472-4 ·PMID:38305995
other 2024
doi:10.1007/s43032-024-01518-7 ·PMID:38561472

Endometriosis (EMT) -related infertility has been a challenge for clinical research. Many studies have confirmed that abnormal alterations in the immune microenvironment and glycolysis are instrumental in causing EMT-related infertility. Re…

observational 2024
doi:10.1007/s43032-024-01569-w ·PMID:38653856

Endometriosis, affecting approximately 10% of reproductive-aged women globally, poses significant challenges, including chronic pelvic pain, dysmenorrhea, and infertility. In low- and middle-income countries like India, accessibility to aff…

meta-analysis 2024
doi:10.1007/s43032-024-01701-w ·PMID:39358652

This study aimed to systematically review existing randomized clinical trials on the effect of dietary interventions on endometriosis. A search was performed on the Cochrane Central Register of Controlled Trials (CENTRAL), Cumulative Index …

case-report 2024
doi:10.1007/s43032-024-01601-z ·PMID:38806998

Endometriosis is often diagnosed in reproductive aged women with spontaneous ovarian activity. Here we described a case of endometriosis diagnosed in a patient with premature ovarian insufficiency (POI) due to prepubertal bone marrow transp…