Advances in therapy

other 2019

Letter to the Editor in Response to "Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally"

doi:10.1007/s12325-019-01195-y ·PMID:31875298

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other 2018

Comparison of Outcomes of Different Postoperative Hormone Therapy in the Treatment of Ovarian Endometriosis: A Brief Report

doi:10.1007/s12325-018-0715-z ·PMID:29873006

INTRODUCTION: Hormone therapy is widely used in the treatment of patients with ovarian endometriosis after surgery, and progestin and gonadotropin-releasing hormone (GnRH) are two of the most widely used hormones. This study aimed to compar…

observational 2018

Real-World Evaluation of Direct and Indirect Economic Burden Among Endometriosis Patients in the United States

doi:10.1007/s12325-018-0667-3 ·PMID:29450864

INTRODUCTION: The prevalence of endometriosis and the need for treatment in the USA has led to the need to explore the contemporary cost burden associated with the disease. This retrospective cohort study compared direct and indirect health…

review 2018

Recognizing Gynecological Cancer in Primary Care: Risk Factors, Red Flags, and Referrals

doi:10.1007/s12325-018-0683-3 ·PMID:29516408

Early diagnosis of symptomatic gynecological cancer is likely to improve patient outcomes, including survival. The primary care practitioner has a key role to play in this-they must recognize the symptoms and signs of gynecological cancer a…

observational 2017

Changes in Healthcare Spending After Diagnosis of Comorbidities Among Endometriosis Patients: A Difference-in-Differences Analysis

doi:10.1007/s12325-017-0630-8 ·PMID:29101714

INTRODUCTION: We sought to characterize changes in healthcare spending associated with the onset of 22 endometriosis-related comorbidities. METHODS: Women aged 18-49 years with endometriosis (N = 180,278) were extracted from 2006-2015 de-i…

rct 2017

Comparing the Administration of Letrozole and Megestrol Acetate in the Treatment of Women with Simple Endometrial Hyperplasia without Atypia: A Randomized Clinical Trial

doi:10.1007/s12325-017-0509-8 ·PMID:28353144

INTRODUCTION: The present study was conducted as a pilot to compare the therapeutic effects and the potential side effects of oral Megestrol acetate and Letrozole in the treatment of simple hyperplasia in perimenopausal women. METHODS: The…

rct 2017

Randomized Controlled Trial of Hyalobarrier® Versus No Hyalobarrier® on the Ovulatory Status of Women with Periovarian Adhesions: A Pilot Study

doi:10.1007/s12325-016-0453-z ·PMID:27900662

INTRODUCTION: Periadnexal adhesions are known to contribute to subfertility. The restoration of the tubo-ovarian anatomy is one the key principles in reproductive surgery, and this involves adhesiolysis. However, adhesion formation/reformat…

observational 2017

Treatment Patterns, Complications, and Health Care Utilization Among Endometriosis Patients Undergoing a Laparoscopy or a Hysterectomy: A Retrospective Claims Analysis

doi:10.1007/s12325-017-0619-3 ·PMID:29039055

INTRODUCTION: Hysterectomy and laparoscopy are common surgical procedures used for the treatment of endometriosis. This study compares outcomes for women who received either procedure within the first year post initial surgery. METHODS: Th…

observational 2016

Factors and Regional Differences Associated with Endometriosis: A Multi-Country, Case-Control Study

doi:10.1007/s12325-016-0366-x ·PMID:27342743

INTRODUCTION: The present study aimed to investigate clinical, lifestyle, and environmental factors associated with endometrioma (OMA) and/or deep infiltrating endometriosis (DIE) as determined by case-control comparison [women with superfi…