Voprosy onkologii

Data on 304 patients with ovarian malignancies (mostly epithelial-72.0%) who had undergone second-look surgery were analysed to develop indications and assess the clinical value of the procedure. Second-look operations were performed 10-22 …

In a group of 811 patients with epithelial malignancies of the ovaries, the diagnostic and therapeutic procedures used were either standard or they involved elements of optimization based on certain objective criteria. The reliability of di…

The paper is concerned with results of a study of clinico-biologic effect of a gestagen norsteroid drug--norcolut--on solitary and combined lesions of the endo- and myometrium. Four hundred and thirty-four patients of reproductive age with …

The clinico-morphological data on the results of five- and ten-year follow-up of 228 patients suffering "borderline" epithelial (serous, mucinous and endometrioid) ovarian tumors were studied. Considerations of choice of optimal treatment p…

The study was concerned with morphological criteria for assessing the degree of differentiation of ovarian cancer and establishing their relationship with clinical course in 323 patients. The degree of ovarian cancer differentiation was fou…

Clinical course versus morphological data on the level of tumor cell differentiation was studied in 323 cases of cancer of the ovaries. Level of cell differentiation proved to be of prognostic value, since it appeared to influence prognosis…

Clinico-morphological peculiarities of endometrioid cystadenocarcinoma of the ovaries (105 cases) were compared with those of a more frequent serous one. Hyperestrogenism was more frequent in endometrioid cystadenocarcinoma, metastases, asc…

Clinico-morphological features of 228 proliferating epithelial ovarian tumors of various histological patterns were studied. The group under study consisted of 135 serous (59.2%), 54 mucinous (23.7%) and 39 endometroid cystadenomas (17.1%).…

The paper discusses the results of a retrospective analysis of the data on the evaluation of the efficacy of chemotherapy as an adjuvant to surgery performed in 167 patients with stage I ovarian cancer who were treated at the Institute and …

The data on 41 patients with epithelial malignant tumors of the ovaries, who received sarcolysin at different stages of combined treatment, were analyzed. The following factors of therapeutic effect of sarcolysin were established: age of 41…

The paper presents the results of intratumoral chemotherapy of 32 cases of single metastases of stage III-IV ovarian cancer into the Douglas pouch. The metastases were detected at different stages after primary treatment. Thiotepa, cyclopho…

Such features as single-phase cycling, endocrine infertility, endometriosis concomitant endometrial hyperplasia, endometrial carcinoma and endometriosis with concomitant uterine myoma and proliferative processes in the mammary glands as wel…

A clinicopathological study of 152 autopsied cases of ovarian cancer was carried out. Metastases in lymph nodes ranked third (57.9%), following lesions in the peritoneum (92.1%) and greater omentum (79.6%). Metastases in lymph nodes were fo…

Electron-microscopy was used to study the intraoperative material in 37 patients with serous (24), mucinous (8) and endometroid (5) ovarian neoplasms of benign, boundary and malignant forms. It was shown that the polysome-lamellae complexes…

The author reports epidemiological and clinical data on 739 patients with benign epithelial ovarian tumors of various histotypes. Serous cystadenomas were found in 46%, mucinous--in 25.3%, endometroid--in 20%, mixed epithelial--in 6.7%, the…

The study is based on the authors' personal material (81 patients). It was found that malignant endometrioid ovarian tumors invade metastatically the greater omentum more rarely than serous carcinomas--in 42% according to our findings, vers…

The study was based on examination of cytographs of the Douglas space needle biopsy specimens and histological preparations of the operative material of 150 patients, 19 of them showing ovarian endometriosis. The results of correlating hist…

Using electron microscopy the authors have studied the operation material of 15 patients with serous (9 cases) and endometrioid (6 cases) ovarian neoplasms. It was demonstrated that the epithelium of endometrioid neoplasms differs from that…

The author reports 35 personal observations of endometrioid ovarian neoplasms with cacific inclusions. It was found that calcification is characteristic not only of serous neoplasms. It is not infrequently noted in endometriosis, endometrio…

Under study was the intraoperative material from 32 patients with endometrial ovarian neoplasms having an epidermoid structure. Epidermoid foci were found to be pathognomonic only for the endometrioid epithelium. This fact may be used for t…

The author has based his study on the operation material from 110 patients. It was found that endometrioid ovarian neoplasms appear and develop against the background of the generation apparatus atrophy, microfollicular cysts and the comato…

In the literature, the problems of the histology, morphogenesis and malignant transformation of ovarian endometriosis are being elucidated but rather contradictory. The author's personal study is based on the examination of operative materi…

An attempt was made to differentiate various types of development of corpus uteri adenomatosis in the clinico-morphological aspect. Three forms of adenomatosis were differentiated: focal, diffuse and malignant adenomatosis. Studies of curet…