Voprosy onkologii

Surgery is the cornerstone of the treatment of endometrial cancer. With introduction of new technologies the laparoscopic intervention becomes increasingly popular for treatment of endometrial cancers. Forty five patients with endometrial c…

Data on 304 patients with ovarian malignancies (mostly epithelial-72.0%) who had undergone second-look surgery were analysed to develop indications and assess the clinical value of the procedure. Second-look operations were performed 10-22 …

In a group of 811 patients with epithelial malignancies of the ovaries, the diagnostic and therapeutic procedures used were either standard or they involved elements of optimization based on certain objective criteria. The reliability of di…

Ten-year experience with ultrasonography was gained at an outpatient center. Within this period, 27000 examinations were performed in 11996 females. The credibility of the method in diagnosing endometrial pathology was 85.8%. Cancer morbidi…

The paper is concerned with results of a study of clinico-biologic effect of a gestagen norsteroid drug--norcolut--on solitary and combined lesions of the endo- and myometrium. Four hundred and thirty-four patients of reproductive age with …

The clinico-morphological data on the results of five- and ten-year follow-up of 228 patients suffering "borderline" epithelial (serous, mucinous and endometrioid) ovarian tumors were studied. Considerations of choice of optimal treatment p…

Colonic tumor dissemination to the ovaries was registered in 3%. The likelihood of such dissemination in locally-advanced cancer of the sigmoid colon was higher which in turn supports the hypothesis on colonic tumor dissemination to the ova…

The study was concerned with morphological criteria for assessing the degree of differentiation of ovarian cancer and establishing their relationship with clinical course in 323 patients. The degree of ovarian cancer differentiation was fou…

It was shown that the risk for endometrial cancer development in uterine myoma increases 43-fold in cases of diabetes mellitus, hypertension and obesity, 20-fold in adnexitis, 15-fold in hyperplastic endometrial lesions and 9.8-fold in the …

Clinical course versus morphological data on the level of tumor cell differentiation was studied in 323 cases of cancer of the ovaries. Level of cell differentiation proved to be of prognostic value, since it appeared to influence prognosis…

The study was concerned with the condition of the endometrium and myometrium in relation to the histological pattern of ovarian tumor and tumor-like growth and patient's age. Polyps, glandular atypical hyperplasia and endometrial adenocarci…

Low-fractionated intracavitary gamma-therapy from the AGAT-B installation was given to 212 patients as the initial component of combined treatment. The treatment was well tolerated and was followed by a partial regression of tumor. It did n…

The results of a two-stage hormonal treatment of 62 cases of atypical hyperplasia of the endometrium were analysed. Within the first 6 months, patients received 24.0-28.0 g of hydroxyprogesterone capronate each. Six courses of steroid contr…

Clinico-morphological peculiarities of endometrioid cystadenocarcinoma of the ovaries (105 cases) were compared with those of a more frequent serous one. Hyperestrogenism was more frequent in endometrioid cystadenocarcinoma, metastases, asc…

Clinico-morphological features of 228 proliferating epithelial ovarian tumors of various histological patterns were studied. The group under study consisted of 135 serous (59.2%), 54 mucinous (23.7%) and 39 endometroid cystadenomas (17.1%).…

The paper discusses the results of a retrospective analysis of the data on the evaluation of the efficacy of chemotherapy as an adjuvant to surgery performed in 167 patients with stage I ovarian cancer who were treated at the Institute and …

The data on 41 patients with epithelial malignant tumors of the ovaries, who received sarcolysin at different stages of combined treatment, were analyzed. The following factors of therapeutic effect of sarcolysin were established: age of 41…

The paper presents the results of intratumoral chemotherapy of 32 cases of single metastases of stage III-IV ovarian cancer into the Douglas pouch. The metastases were detected at different stages after primary treatment. Thiotepa, cyclopho…

Such features as single-phase cycling, endocrine infertility, endometriosis concomitant endometrial hyperplasia, endometrial carcinoma and endometriosis with concomitant uterine myoma and proliferative processes in the mammary glands as wel…

A clinicopathological study of 152 autopsied cases of ovarian cancer was carried out. Metastases in lymph nodes ranked third (57.9%), following lesions in the peritoneum (92.1%) and greater omentum (79.6%). Metastases in lymph nodes were fo…

Electron-microscopy was used to study the intraoperative material in 37 patients with serous (24), mucinous (8) and endometroid (5) ovarian neoplasms of benign, boundary and malignant forms. It was shown that the polysome-lamellae complexes…

The author reports epidemiological and clinical data on 739 patients with benign epithelial ovarian tumors of various histotypes. Serous cystadenomas were found in 46%, mucinous--in 25.3%, endometroid--in 20%, mixed epithelial--in 6.7%, the…