BMJ open

BMJ Open · ISSN (e) 2044-6055 · 292 papers in corpus
other 2022
doi:10.1136/bmjopen-2022-063030 ·PMID:35831058

INTRODUCTION: Conventional intracytoplasmic sperm injection (ICSI) is a widely used treatment for couples with severe male infertility. However, there are controversies regarding the selection and the damage to gametes during the ICSI proce…

other 2022
doi:10.1136/bmjopen-2021-052043 ·PMID:35715184

INTRODUCTION: Infertility is a common complication of endometriosis. While in vitro fertilisation-embryo transfer (IVF) successfully treats endometriosis-associated infertility, there is some evidence that pregnancy rates may be diminished …

other 2022
doi:10.1136/bmjopen-2021-052192 ·PMID:35105623

INTRODUCTION: Medical treatment is a less invasive alternative to surgical management of missed miscarriage. Studies have shown that pretreatment with mifepristone can increase the complete abortion rate in management of first-trimester mis…

other 2022
doi:10.1136/bmjopen-2022-064073 ·PMID:36241351

INTRODUCTION: Endometriosis is a common gynaecological disease associated with pelvic pain and subfertility. There are no non-invasive diagnostic tests, medical management requires suppression of oestrogens and surgical removal is associate…

qualitative 2022
doi:10.1136/bmjopen-2021-060107 ·PMID:35768082

ObjectiveThis study aimed to better understand the psychological experiences of inpatients with acute pancreatitis (AP).DesignWe used a qualitative descriptive study design to capture patients with AP's thoughts, feelings and behavioural re…

qualitative 2022
doi:10.1136/bmjopen-2022-062852 ·PMID:36414289

OBJECTIVES: Recurring cystitis (RC) is a common complaint among women. It has a significant impact on patients' quality of life. The physical discomfort and psychological distress related to RC are rarely addressed and women's needs in term…

other 2022
doi:10.1136/bmjopen-2022-063572 ·PMID:35851028

INTRODUCTION: Endometriosis is a common gynaecological disease affecting around 10% of fertile-aged women, causing severe pain symptoms. Deep endometriosis is defined as endometriotic implants that infiltrate the underlying organs more than…

other 2022
doi:10.1136/bmjopen-2021-060409 ·PMID:35835531

INTRODUCTION: The lifetime risk of women undergoing surgery for the presence of benign ovarian pathology in the UK is 5%-10%. Despite minimally invasive surgical techniques, evidence suggests a number of healthy ovarian follicles and tissue…

observational 2022
doi:10.1136/bmjopen-2021-059934 ·PMID:35450914

OBJECTIVE: To assess the time to development of anaemia and its predictors among women of reproductive-age receiving antiretroviral therapy (ART) in public hospitals, Southwest Ethiopia. DESIGN: Hospital-based retrospective follow-up study…

meta-analysis 2022
doi:10.1136/bmjopen-2021-051489 ·PMID:35473741

PURPOSE: This study aims to review the literature and perform a meta-analysis to determine if the presence of a corpus luteum has an impact on treatment outcomes in thaw cycles, where blastocyst embryos are transferred. METHOD: PUBMED, EMB…

2022

Introduction Natural Orifice Transluminal Endoscopic Surgery is a minimal invasive technique using natural body orifices like the vagina. Benefits of a vaginal assisted NOTES hysterectomy (VANH) are no visible scars, less blood loss, shorte…

observational 2022
doi:10.1136/bmjopen-2022-060995 ·PMID:36115675

OBJECTIVES: The COVID-19 pandemic has negatively impacted mental health worldwide but there is paucity of knowledge regarding the level of change in mental health in people with a medical condition (physical/psychiatric). The objectives of …

other 2021
doi:10.1136/bmjopen-2020-046927 ·PMID:34233986

OBJECTIVES: The anti-Mullerian hormone (AMH) test has been promoted as a way to inform women about their future fertility. However, data consistently show the test is a poor predictor of natural fertility potential for an individual woman. …

other 2021
doi:10.1136/bmjopen-2020-041254 ·PMID:33452191

OBJECTIVE: There are many uncertainties surrounding the aetiology, treatment and sequelae of hyperemesis gravidarum (HG). Prioritising research questions could reduce research waste, helping researchers and funders direct attention to those…

observational 2021
doi:10.1136/bmjopen-2020-046891 ·PMID:34949602

OBJECTIVE: Both physical diseases such as infection and chronic pain and psychological disorders such as depression have been associated with herpes zoster (HZ) reactivation. However, the relationship between de Quervain syndrome (DQS), a p…

observational 2021
doi:10.1136/bmjopen-2020-046607 ·PMID:34162647

OBJECTIVE: The association between use of birth control pills and thyroid function in women has not ever been well studied, but potential risk has been implicated by small sample-sized studies. We aimed to determine this association using a…

other 2021
doi:10.1136/bmjopen-2021-053971 ·PMID:34697123

INTRODUCTION: Approximately 30% of people with long-term physical health conditions (LTCs) experience mental health problems, with negative consequences and costs for individuals and healthcare services. Access to psychological treatment is…

observational 2021
doi:10.1136/bmjopen-2021-050931 ·PMID:34281932

PURPOSE: To generate a large cohort of children born after assisted reproductive technology (ART) in the UK between 1992 and 2009, their naturally conceived siblings (NCS) and matched naturally conceived population (NCP) controls and linkin…

other 2021
doi:10.1136/bmjopen-2020-044933 ·PMID:33757952

PURPOSE: A multicentre prospective cohort study, known as the Chinese Pregnant Women Cohort Study (CPWCS), was established in 2017 to collect exposure data during pregnancy (except environmental exposure) and analyse the relationship betwee…

other 2021
doi:10.1136/bmjopen-2020-045770 ·PMID:34462279

INTRODUCTION: Recently, the rate of caesarean sections (CS) worldwide has risen and CS-associated complications such as niche have increased substantially. Until now, evidence-based clinical guidelines for the treatment of niche-related sym…

other 2021
doi:10.1136/bmjopen-2021-049109 ·PMID:34620658

INTRODUCTION: Achieving gross total resection and endocrine remission in pituitary neuroendocrine tumours (PitNET) can be challenging, especially in PitNETs with cavernous sinus (CS) invasion, defined as a Knosp grade of 3 or 4. A potential…

observational 2021
doi:10.1136/bmjopen-2020-043786 ·PMID:33903142

INTRODUCTION: Birth spacing is a critical pathway to improving reproductive health. WHO recommends a minimum of 33-month interval between two consecutive births to reduce maternal, perinatal, infant morbidity and mortality. Our study evalua…

other 2021
doi:10.1136/bmjopen-2021-054896 ·PMID:34880026

INTRODUCTION: Endometriosis can cause chronic pain and subfertility thereby negatively affecting quality of life (QoL). Surgical removal of endometriosis lesions leads to improved health-related QoL, although not to the level of QoL of heal…

other 2021
doi:10.1136/bmjopen-2021-050248 ·PMID:34716161

INTRODUCTION: Adenomyosis can adversely reduce chances of pregnancy in couples undergoing assisted conception. We aim to evaluate the effect of two different downregulation protocols on the reproductive outcomes in women with moderate and s…

other 2021
doi:10.1136/bmjopen-2021-055039 ·PMID:34556520

INTRODUCTION: Current treatments for chronic pain (eg, opioids) can have adverse side effects and rarely result in resolution of pain. As such, there is a need for adjuvant analgesics that are non-addictive, have few adverse side effects an…