Journal of neuroinflammation

J Neuroinflammation · ISSN (e) 1742-2094 · 4 papers in corpus
article 2023
doi:10.1186/s12974-023-02713-0 ·PMID:36879305

BACKGROUND: Chronic pelvic pain (CPP) is a common symptom of endometriosis. Women with endometriosis are also at a high risk of suffering from anxiety, depression, and other psychological disorders. Recent studies indicate that endometriosi…

article 2021
doi:10.1186/s12974-020-02066-y ·PMID:33673857

BACKGROUND: As a classic innate immunity pathway, Toll-like receptor 4 (TLR4) signaling has been intensively investigated for its function of pathogen recognition. The receptor is located not only on immune cells but also on sensory neurons…

review 2020
doi:10.1186/s12974-020-01752-1 ·PMID:32145751

Abstract Endometriosis is a chronic inflammatory disease. Pain is the most common symptom in endometriosis. Endometriosis-associated pain is caused by inflammation, and is related to aberrant innervation. Although the specific mechanism bet…

review 2017
doi:10.1186/s12974-017-0828-3 ·PMID:28288663

Dysregulation of the immune system in endometriotic milieus has been considered to play a pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber infiltration are the two major characteristics of this aberr…