QJM : monthly journal of the Association of Physicians

Scar sarcoidosis is a form of cutaneous sarcoidosis characterized by granulomatous inflammation arising within pre-existing scars or sites of previous trauma. These lesions may develop years after the initial injury and can mimic foreign bo…

IntroductionSpontaneous pneumothorax recurs in 30-54% of patients without surgery. Identifying individuals likely to suffer a recurrence, who might benefit from pre-emptive surgery, is challenging. Previous meta-analysis suggested a relatio…

BACKGROUND: There is limited comprehensive evidence on the potential association between early menarche and subsequent health outcomes. AIM: To evaluate the existing evidence for the association of early menarche with later health outcomes…

We present a 44-year-old woman with no personal history of relevance but for a heterozygous mutation G1691A of the gene of Leiden factor V. Her history starts 2 years ago with two consecutive, 1 month apart, right pneumothoraces that were d…

In the design of clinical trials, sample size determination is usually undertaken by statisticians and clinicians. It is rare for health economists to be involved in this aspect of trial design. However, there are a number of outcome change…