Health science reports

BACKGROUND AND AIMS: Familial Mediterranean Fever (FMF) is a monogenic autoinflammatory disease caused by mutations in the MEFV gene, resulting in recurrent inflammatory episodes and a risk of developing amyloidosis. Although its pathophysi…

BACKGROUND AND AIMS: Ovarian reserve markers are reported to differ across ethnic groups, though the sources of this variation are unclear. We aimed to document this variation and examine the environmental, nutritional, and sociocultural fa…

BACKGROUND AND AIMS: The present review aims to ascertain whether reproductive disorders are associated with specific physical, mental, personality, and social traits. This information may be used to support or reject the hypothesis on the …

INTRODUCTION: Menstrual disorders and abnormal uterine bleeding are among the most frequent reasons for gynecological consultation among women, especially young women. METHOD: Observational multicenter study with young women from Spain dur…

BACKGROUND AND AIMS: Hysterectomy may lead to psychological and sexual challenges that extend beyond physical recovery. This randomized controlled trial evaluated the effect of psychosexual counseling based on the Schover bio-psycho-social …

BACKGROUND: Premature ovarian insufficiency (POI) is defined as the loss of ovarian activity before age 40, resulting in hypoestrogenism, hypergonadotropic hypogonadism, amenorrhea, and infertility, significantly impacting women's reproduct…

BACKGROUND AND AIMS: To evaluate the transition of Carbohydrate antigen 125 (CA-125) from an ovarian tumor marker to a versatile indicator of systemic congestion and fluid overload. METHODS: A literature review (1984-2025) was conducted us…

BACKGROUND AND AIMS: Ovarian cancer is a primary contributor to cancer-related deaths among women and holds a position among the most common gynecological malignancies worldwide. While hypertension has been identified as a potential risk fa…

BACKGROUND AND AIMS: Effective utilization of perioperative blood transfusions can reduce costs and minimize blood waste. This study aimed to audit the appropriateness of current blood utilization practices in gynecological surgeries, chara…

BACKGROUND: Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti-inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This …

BACKGROUND AND AIMS: Uterine artery embolization (UAE) is an effective minimally invasive treatment for symptomatic fibroids; however, post-procedural pain remains a major limitation. Intra-arterial lidocaine administration has shown incons…

BACKGROUND AND AIMS: Sleep disturbances are increasingly recognized in women with polycystic ovary syndrome (PCOS), but the evidence remains inconsistent. We conducted a meta-analysis to evaluate objective sleep abnormalities and subjective…

BACKGROUND AND AIMS: Dysmenorrhea is a common gynecological condition affecting young women and is associated with reduced academic performance and quality of life. This study aimed to determine the prevalence of dysmenorrhea and examine it…

BACKGROUND AND AIMS: Dysmenorrhea is a common gynaecological condition among female adolescents and affects students' well-being in Ghana. This study assessed dysmenorrhea prevalence, effects, and coping mechanisms among adolescent girls in…

BACKGROUND AND AIMS: Xanthogranulomatous endometritis (XGE) is a rare, chronic inflammatory disease that could mimic endometrial malignancy. While ultrasound is a primary imaging tool in gynecology, a comprehensive synthesis of its features…

BACKGROUND AND AIMS: Endometriosis is associated with oxidative stress and heavy metal accumulation. This study evaluated whether N-acetylcysteine (NAC) reduces serum heavy metals and improves lipid profiles in women with endometriosis unde…

BACKGROUND AND AIMS: Dysbiosis is the substitution of the normal gut flora with a dysfunctional array of organisms that influences the outcome of multiple inflammatory pathways, contributing to systemic inflammation and various disease stat…

BACKGROUND AND AIMS: Endometriosis is a condition in which tissue similar to the endometrium grows outside the uterus. Angiogenesis plays an important role in endometriosis development. Bioinformatics analysis indicates that miR-410-3p is i…

BACKGROUND AND AIMS: Infertility is a significant public health issue worldwide, and endometriosis is a major contributor to infertility, impacting 6%-10% of reproductive-aged women. The objective of the study is to assess the relationship …

BACKGROUND AND AIMS: The development of prostaglandins and antiprogestins revolutionized medical abortion by providing effective nonsurgical options for terminating pregnancy. Although both strategies are accepted in practice, variations in…

BACKGROUND: Female infertility is a global health issue however, its link with genital infections is often overlooked due to asymptomatic nature of infections. Delayed diagnosis and treatment due to absence of reliable point-of-care (POC) t…

BACKGROUND AND AIMS: The COVID-19 pandemic has significantly affected public health worldwide. This study applies a novel Robust Bayesian Model Averaging-Publication Selection Model Averaging method (RoBMA-PSMA) to address publication bias …

BACKGROUND AND AIMS: Vitamin D deficiency is a common nutritional problem in women of childbearing age. Polycystic ovary syndrome (PCOS) is a frequent endocrine disorder associated with various metabolic complications. While meta-analyses o…

BACKGROUND AND AIMS: Intraperitoneal adhesions are a common complication after gynecologic surgery, leading to infertility, chronic pelvic pain, bowel obstruction, and surgical complications. Hyaluronic acid gel functions as a physical barr…