BMC pregnancy and childbirth

BACKGROUND: Placental abruption is one of the most severe complications during pregnancy, and its associated risk factors remain incompletely understood and somewhat controversial. METHODS: This study conducted a systematic search of the P…

OBJECTIVE: This study aimed to develop a machine learning (ML) model integrated with SHapley Additive exPlanations (SHAP) analysis to predict postpartum hemorrhage (PPH) following vaginal deliveries, offering a potential tool for personaliz…

BACKGROUND: Surgical intervention is the main treatment for endometriosis, and effective postoperative care is crucial for long-term health. This study examined the knowledge, attitudes, and practices (KAP) of patients with endometriosis in…

BACKGROUND: Melatonin (MT) is involved in the regulation of various important biological processes related to reproduction. Many studies have investigated the effects of MT supplementation on outcomes following assisted reproductive technol…

BACKGROUND: The success of in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) in endometriosis patients varies widely, and predicting the likelihood of achieving a live birth remains a clinical challenge. This study aims t…

INTRODUCTION: The aim of the study was to explore the impact of the clinical and embryological factors on the pregnancy outcome of FET cycle, while determining the applicability range for the primary predictor. METHODS: A total of 4395 FET…

BACKGROUND: Endometriosis is a common cause of infertility in women of reproductive age, and many affected women require assisted reproductive technology (ART) to conceive. It is also associated with increased risks of adverse obstetric com…

BACKGROUND: To investigate the optimal periendometrial zone (PEZ) in ultrasound (US) images and assess the performance of ultrasound radiomics in predicting the outcome of frozen embryo transfer (FET). METHODS: This prospective study had 4…

BACKGROUND: Ectopic Pregnancy (EP) is a type of pregnancy where the developing blastocyst implants in a location other than the endometrial cavity. The aim of study was developing predictive models that could improve the accuracy of identif…

BACKGROUND: Congenital uterine anomalies are associated with adverse reproductive outcomes, yet the impact of the arcuate uterus remains unclear due to limited sample sizes and inconsistent findings in previous studies. We utilized a large …

BACKGROUND: Multimorbidity in pregnancy increases health risks to women and babies, and creates challenges for services. The aim of this study was to explore the prevalence and patterns of maternal multimorbidity in a UK population. METHOD…

BACKGROUND: Gestational Diabetes Mellitus (GDM) is a prevalent metabolic condition during pregnancy that can affect up to 24.9% of pregnancies in the United Arab Emirates (UAE). GDM can impair the mother's Quality of life (QOL) due to physi…

OBJECTIVE: To systematically review studies on reproductive outcomes following fertility-sparing interventions. METHODS: Various electronic databases were searched and studies reporting reproductive outcomes following fertility-sparing int…

OBJECTIVE: A septate uterus is a common congenital anomaly often identified during infertility evaluations and is associated with adverse reproductive outcomes. Hysteroscopic septum resection is widely recognized as a standard, safe, and ef…

BACKGROUND: Diminished ovarian reserve refers to the decrease in the quantity and quality of oocytes in the ovary which may cause poor fertility outcomes even with the help of assisted reproductive techniques. Most patients will undergo mul…

OBJECTIVE: In order to examine the impact of belimumab on recurrent spontaneous abortion (RSA) women exhibiting B lymphocyte dysfunction. METHODS: This study conducted a retrospective case-control analysis of RSA patients with confirmed B …

BACKGROUND: Intramural pregnancy (IMP) is a subtype of ectopic pregnancy that can lead to life-threatening uterine rupture and severe hemorrhage. However, the clinical manifestations of IMP are nonspecific, making early clinical recognition…

OBJECTIVE: Intrauterine Adhesions (IUA), including Asherman's Syndrome, are a significant cause of female infertility, while stem cell interventions emerge as a promising therapeutic strategy. This meta-analysis aims to systematically evalu…

Endometriosis is a chronic inflammatory condition, typically associated with pelvic pain and menorrhagia, affecting 10% of women of reproductive age. Inflammation is known to contribute to pregnancy complications, including preterm birth. R…

BACKGROUND: Intrauterine insemination (IUI) also found that this experience was associated with anxiety. Therefore, measures must be taken to reduce or eliminate the pain and anxiety associated with it. OBJECTIVES: This study investigated …

BACKGROUND: Tubal ectopic pregnancy (TEP) is a common and serious obstetric complication with unclear pathogenesis. This study aims to use single-cell RNA sequencing (scRNA-seq) to analyze immune cell composition and functional changes in i…

BACKGROUND: Adenomyosis is increasingly recognized as a significant factor affecting fertility, particularly in the context of assisted reproductive technologies (ART). This study aimed to assess the independent impact of adenomyosis on int…

BACKGROUND: Several studies have demonstrated that pre-treatment with long-acting Gonadotropin-Releasing Hormone agonists (GnRHa) can significantly enhance the clinical pregnancy rate among recurrent implantation failure (RIF) patients. Inv…

BACKGROUND: Endometriomas may adversely affect fertility; however, the necessity of its surgical management is a controversial subject. The aim of this study was to compare the time to conception, mode of conception, and pregnancy outcomes …

OBJECTIVE: To investigate whether the previous spontaneous miscarriages affect the cycle outcomes in in vitro fertilization and embryo transfer (IVF-ET). METHODS: Comparisons were made on the cycle characteristics and outcomes between pati…