BMC pregnancy and childbirth

BACKGROUND: Hereditary Hemorrhagic Telangiectasia (HHT) is a rare vascular disorder with mucocutaneous telangiectasia. Hormones are hypothesized to play a role in reducing bleeding in these patients; however, clear evidence is currently lac…

BACKGROUND: Serum beta-human chorionic gonadotropin (β-hCG) hormone is a well-established biomarker used for pregnancy monitoring and prognosis in in vitro fertilization (IVF) cycles. After embryo transfer, a high serum β-hCG level with a p…

OBJECTIVE: To investigate the relationship between third-trimester antenatal depression (AND) and the number of pregnancies, considering the possible moderating role of dysmenorrhea. METHODS: A total of 1,178 pregnant women in their third t…

PURPOSE: Embryo cryopreservation plays an essential role in assisted reproductive technology (ART). Vitrification has gradually replaced slow-freezing of embryos. In this study we investigated the effects of embryo vitrification on neonatal…

BACKGROUND: We aimed to evaluate the risk of perinatal complications in subsequent pregnancies after different types of myomectomy, viz. open, laparoscopic, or hysteroscopic. Moreover, we investigated whether the time interval from myomecto…

BACKGROUND: With rising rates of delayed childbearing in China, clinical decision-making for advanced-age primiparas (≥ 35 years) is challenging, often leading to unnecessary cesarean sections or failed labor trials. This study aimed to dev…

AIM: To evaluate the predictive value of serum beta-human chorionic gonadotropin (β-hCG) measured at 11-14 days after frozen-thawed embryo transfer (FET) for clinical pregnancy, and to explore the potential associations of blastocyst transf…

BACKGROUND: To evaluate whether progesterone-induced changes in endometrial thickness (EMT) affect singleton infant outcomes during frozen-thawed embryo transfer (FET) cycles. METHODS: This retrospective study analyzed 6,331 singleton live…

BACKGROUND: To investigate the associations of reproductive tract and follicular fluid microbiota composition, microbial diversity, and probiotic interventions with pregnancy outcomes after in vitro fertilization (IVF) or intracytoplasmic s…

BACKGROUND: Benzodiazepine use during pregnancy remains common despite guidelines discouraging it, except for short-term treatment of severe anxiety or agitation. Previous studies have suggested an increased risk of miscarriage after in ute…

BACKGROUND: Ovarian pregnancies at advanced gestational ages are exceedingly rare in clinical practice. The infrequency of this condition, coupled with the nonspecific nature of its symptoms and signs, renders preoperative diagnosis extreme…

BACKGROUND: Multiple myeloma (MM) in association with pregnancy is a rare event, and a consensus is lacking. It is urgent to increase the awareness of investigations required for a suspected diagnosis of MM during pregnancy and optimise its…

BACKGROUND: Diffuse uterine leiomyomatosis (DUL) is a rare condition characterized by innumerable leiomyomas (fibroids) diffusely replacing the myometrium, often leading to severe infertility due to distortion of the uterine cavity. Althoug…

OBJECTIVE: This study aims to identify the most diagnostically valuable features among the 11 MRI features of Placenta accreta spectrum (PAS) described in the joint consensus statement by the Society of Abdominal Radiology (SAR) and the Eur…

BACKGROUND: Women born in Somalia who have migrated to Sweden have increased risks of complications related to pregnancy and childbirth. Swedish-Somali women are, compared to women born in Sweden, less likely to contact healthcare for decre…

BACKGROUND: Women with advanced maternal age (AMA) face a significant decline in embryo euploidy rates, leading to reduced fertility and increased risks of adverse pregnancy outcomes. While preimplantation genetic testing for aneuploidy (PG…

BACKGROUND: Cervical pregnancy (CP) is a rare but life-threatening ectopic gestation with high risk of catastrophic hemorrhage during evacuation. Uterine artery embolization (UAE) combined with dilation and curettage (D&C) has been proposed…

BACKGROUND: A uterine niche (cesarean section scar defect), defined as an indentation ≥ 2 mm in the myometrium at the site of a previous cesarean scar, reflects impaired myometrial healing after cesarean delivery. Its prevalence increases w…

BACKGROUND: With the rising rate of cesarean section delivery worldwide, the development of cesarean scar diverticulum (CSD) is increasingly observed, with a prevenance ranging from 24% to 70%. CSD is associated with abnormal uterine bleedi…

OBJECTIVE: To identify the key factors associated with biochemical pregnancy loss (BPL) following single blastocyst transfer in frozen embryo transfer (FET) cycles utilizing hormone replacement therapy (HRT). METHODS: This retrospective co…

BACKGROUND: Uterine rupture is rare and life-threatening for both mothers and newborns. This study aimed to explore the clinical manifestation, site of rupture, obstetric risk factors, maternal and neonatal complications, and birth outcomes…

OBJECTIVE: Preterm birth is a major global health issue, with higher rates observed in pregnancies following assisted reproductive technology (ART). This study aimed to develop and validate via the validation set a prediction model for pret…

BACKGROUND: The risk of preterm birth (PTB) is associated with maternal hyperglycemia but differs by combinations of abnormal oral glucose tolerance test (OGTT) values. However, the potential pathway by which maternal hyperglycemia affects …

BACKGROUND: Adenomyosis is thought to be associated with adverse perinatal outcomes. This study aimed to assess the relationship between pre-pregnancy uterine volume and preterm birth in singleton gravid women with adenomyosis. METHODS: We…

BACKGROUND: Insulin resistance (IR) is a common pathophysiologic feature in patients with polycystic ovary syndrome (PCOS). However, there have been no studies investigating the association of IR surrogates with pregnancy outcomes in women …