Leiomyoma is the most common benign tumor of the female genital tract. It may develop subserous, intramural, or submucous. The submucous subtype accounts for 5% of all cases, and it may become pedunculated or prolapse outside the uterine ca…
Hysteroscopic myomectomy is the first-line treatment for the removal of submucosal myoma in women facing fertility requirements. However, in the face of large diameter type 2 submucosal myoma, patients are at greater risk of complications s…
BACKGROUND: Endometriosis (EMs) is a benign gynecological disorder that exhibits several malignant characteristics, including proliferation and angiogenesis. N6-methyladenosine (m6A) modification plays a crucial role in regulating RNA splic…
OBJECTIVE: Pelvic organ prolapse (POP) present a significant global health burden, yet effective therapeutic targets remain limited. This study aims to identify potential disease-modifying agents for POP and provide insights to guide the de…
AIM: Polycystic ovary syndrome (PCOS) is a common endocrine disorder with high incidence. It has been reported that patients with PCOS are at great risk of developing endometrial cancer (EC). Our study was aimed to analyze the shared gene s…
Incarceration of the gravid uterus (IGU) is a rare and serious condition associated with significant maternal and fetal morbidities. Its occurrence in women with a history of cesarean section (CS) poses a great challenge to obstetricians. W…
BACKGROUND: Insomnia is increasingly emerging as a significant concern in public health, with a longstanding emphasis on its relationship with overall well-being. Nevertheless, few research has been devoted to investigating the relationship…
INTRODUCTION: Effective ovarian stimulation and luteal phase support (LPS) are key factors for the success of in vitro fertilization and embryo transfer (IVF-ET) The present multicenter randomized trial evaluates whether adding Gushen Antai…
BACKGROUND: Uterine prolapse (UP), a subtype of pelvic organ prolapse (POP), frequently coexists with urinary tract infections (UTIs) and lower urinary tract symptoms (LUTS), including urinary frequency (UF), urinary incontinence (UI), and …
PURPOSE: Emerging evidence suggests that an abnormal endometrial microbiota may be a potential factor contributing to recurrent pregnancy loss (RPL). This study aimed to characterize the endometrial microbiota in patients with RPL and to ex…
Menstrual health is increasingly framed as a multidimensional public issue intersecting with health, education, and gender equality. Yet, national research landscapes remain uneven, shaped by structural neglect, epistemic silences, and soci…
PURPOSE: Premature ovarian insufficiency (POI) is a common late effect of chemotherapy among survivors of adolescent and young-adult cancer (AYAC). Given on the widespread use of Chinese herbal medicine (CHM) in restoring individual health,…
BACKGROUND: Gestational Diabetes Mellitus (GDM) is defined as impaired glucose intolerance resulting in hyperglycemia. SIRT1 deficiency and single nucleotide polymorphisms (SNPs) were also related to diabetes. No documented studies were car…
BACKGROUND: Endometriosis (EMS) is characterized by the occurrence, growth, infiltration, and recurrent bleeding of endometrial tissue outside the uterus. Recent studies have revealed a close association between Neutrophil Extracellular Tra…
OBJECTIVE: This investigation sought to determine optimal prognostic indicators and develop an implementable predictive framework for estimating live birth probabilities in subfertile individuals receiving gonadotropin-releasing hormone ant…
BACKGROUND: Oxidative stress is a critical mediator in ovarian aging, a key process leading to premature menopause (PM), which is defined as menopause before age 40. While the Oxidative Balance Score (OBS), a composite measure of dietary an…
PURPOSE: Endometriosis, a chronic estrogen-dependent condition characterized by the implantation of tissue beyond the uterine cavity, impacts 10% of women of reproductive age. Endometriosis manifests through menstrual discomfort, chronic pe…
PURPOSE: Obstetric rectal buttonhole tear (ORBT) is a rare but serious complication of vaginal delivery, associated with rectovaginal fistula and fecal incontinence. Standardized management protocols are lacking. PATIENTS AND METHODS: We c…
The preconceptional period is crucial for women and couples who desire children as it influences the progress and outcomes of a healthy pregnancy. Preconceptional care is now an accepted paradigm by most healthcare professionals. However, i…
BACKGROUND: Platelet count (PLT) has been identified as a predictor for the development of pelvic adhesions. However, it remains unclear whether platelet-related parameters can also serve as indicators for the occurrence of intrauterine adh…
BACKGROUND: Scar endometriosis is a rare manifestation of extrapelvic endometriosis, characterized by the presence of endometrial tissue within a cesarean section scar. It typically manifests as cyclical pain and swelling at the site of the…
OBJECTIVE: To analyze the relationship and predictive value of Netrin-1 expression and ultrasonic blood flow parameters with the severity of cervical intraepithelial neoplasia (CIN). METHODS: A retrospective analysis was performed on 115 p…
PURPOSE: To investigate the incidence and clinical characteristic of preoperative anemia and its impacts on perioperative outcomes in gynecological inpatients. PATIENTS AND METHODS: We retrospectively collected data from surgical patients …
BACKGROUND: Endometrial thickness measurement (EMT) is not a reliable predictor of clinical pregnancy in Asherman syndrome (AS) patients. The aim of this study is to investigate the impact of endometrial patterns on reproductive outcomes in…
PURPOSE: Recent data comparing natural cycles and artificial cycles in frozen embryo transfer (FET) showed an equivalent LBR when optimized luteal phase support (LPS) was used. Of the suggested methods is the use of GnRH agonists as part of…