International journal of women's health

BACKGROUND: Perimenopausal syndrome (PMS) is common, with more than 70% of perimenopausal women experiencing symptoms such as hot flashes and anxiety. As a key regulator of host physiology, the gut microbiota may play an important role in t…

BACKGROUND: The underlying mechanisms of symptom recurrence or established comprehensive predictive models have not yet elucidated. This study aimed to establish a prediction model for symptom recurrence following focused ultrasound ablatio…

BACKGROUND: The impact of changes in estradiol (E2) levels prior to human chorionic gonadotropin (hCG) administration during controlled ovarian hyperstimulation (COH) on pregnancy and live birth outcomes remains poorly understood. OBJECTIV…

INTRODUCTION: The triple-step method, which comprises transvaginal ultrasound-guided aspiration (TUGA) of cyst fluid, three cycles of a gonadotropin-releasing hormone (GnRH) agonist, and laparoscopic cystectomy, has been proposed for managi…

BACKGROUND: Surgery represents a primary treatment option in selected cases of bowel endometriosis (BE), particularly in patients with significant symptoms or those unresponsive to medical therapy, and effectively improves patients' quality…

BACKGROUND: To evaluate risk factors of overall survival (OS) in patients with advanced epithelial ovarian cancer (AEOC) and establish predictive models for predicting postoperative complete cytoreduction (R0 resection) in AEOC patients to …

BACKGROUND: Uterine leiomyoma (fibroids) is the most common benign tumor in women and the leading indication for hysterectomy, yet medical therapy remains limited and largely hormonal. Whether circulating proteins causally influence fibroid…

BACKGROUND: Endometriosis (EM) and polycystic ovary syndrome (PCOS) are two prevalent endocrine-related gynecological conditions with shared pathophysiological pathways, yet their population-level burden patterns and socioeconomic correlate…

This narrative review first summarizes current treatment strategies and postoperative prevention measures for intrauterine adhesions (IUAs), then discusses prognostic factors associated with pregnancy outcomes and recent advances in predict…

PURPOSE: To investigate the hypothesis that an imbalance between the epithelial adhesion molecule E-cadherin and matrix metalloproteinases (MMPs) underlies the vaginal atrophy associated with menopause. METHODS: This cross-sectional study …

OBJECTIVE: To develop and compare a random survival forest (RSF) model and a Cox regression model-for predicting postoperative recurrence in patients with ovarian endometrioma. METHODS: The primary outcomes of the study were the recurrence…

BACKGROUND: Benign ovarian tumor is a common clinical gynecological disease. Bilateral salpingo-oophorectomy is currently recommended for postmenopausal benign ovarian tumor, and whether the uterus needs to be removed simultaneously is cont…

PURPOSE: To review the incidence and predictive factors of invasive cervical cancer in women who underwent hysterectomy due to an abnormal cervical cytology and/or colposcopy biopsy when cervical conization was considered technically not fe…

PURPOSE: This study aimed to identify adolescent-specific risk factors for endometriosis onset and postoperative recurrence to facilitate early identification and risk stratification. PATIENTS AND METHODS: A retrospective study analyzed ad…

PURPOSE: To characterize the experiences of individuals taking hormonal therapies to manage their symptoms of endometriosis (EM) or uterine fibroids (UF). PATIENTS AND METHODS: This prospective, 16-week observational study enrolled US part…

Endometriosis is often diagnosed several years after the first onset of symptoms; however, the duration of this delay may vary depending on the population studied, the assessment starting point, and the timing of diagnosis. This narrative r…

Abstract: Endometriosis is often diagnosed several years after the first onset of symptoms; however, the duration of this delay may vary depending on the population studied, the assessment starting point, and the timing of diagnosis. This n…

BACKGROUND: Ureteral endometriosis is a rare form of deep infiltrating endometriosis that may lead to silent ureteral obstruction and progressive renal injury. Early diagnosis remains challenging because symptoms are often nonspecific. CAS…

BACKGROUND: Disrupted sleep and shift work are linked to multiple adverse health outcomes, but their association with reproductive endocrine disorders (REDs) and underlying mechanisms remain unclear. Understanding this relationship is cruci…

PURPOSE: This study utilized 1990-2019 data from the Global Burden of Disease (GBD) 2019 study to comprehensively evaluate global and regional temporal trends of endometriosis burden. PATIENTS AND METHODS: Age-standardized incidence rates …

BACKGROUND: Heterotopic pregnancy is a rare but potentially life-threatening gynecologic emergency and is particularly uncommon in natural conceptions. Heterotopic pregnancies are prone to misdiagnosis due to the atypical clinical manifesta…

BACKGROUND: Pyometra is an uncommon gynecologic disorder characterized by the accumulation of pus within the uterine cavity typically resulting from cervical obstruction. Spontaneous perforation of pyometra (SPP) is extremely rare but may r…

PURPOSE: Untreated spontaneous hemoperitoneum in pregnancy (SHiP) can be fatal. It is a rare disorder that occurs during pregnancy. SHiP is associated with a reported maternal mortality rate of 1.7% and a perinatal mortality rate of 26.9%. …