South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

BACKGROUND: Adverse events following COVID-19 vaccination have been studied extensively in recent years. However, there remains a paucity of data directly comparing adverse events among COVID-19 vaccinees and individuals with SARS-CoV-2 inf…

BACKGROUND: Chronic pancreatitis (CP) is defined as a continuing inflammatory disease of the pancreas characterised by irreversible morphological changes, often associated with pain and with the loss of exocrine and/or endocrine function th…

OBJECTIVE: This study was undertaken to assess the spectrum of pelvic pathology observed at laparoscopy in women with chronic pelvic pain, and to compare women with an identifiable cause of pain to those with no visible pelvic pathology, wi…

We assessed the possible role of CA 125 in the monitoring of gonadotrophin-releasing hormone (GnRH) agonist analogue therapy in women with endometriosis and uterine fibroids. Serum concentrations of this cell surface antigen did not correla…

Nine hundred and four patients who visited the Fertility Clinic at Groote Schuur Hospital during 1986 were classified according to infertility factors. In 36% of all couples a male factor was present, while 57% had a tubal, 29% an ovulatory…

A pilot study was undertaken to determine the prevalence of gas in the puerperal endometrial cavity and to determine whether this finding has any relationship to the mode of delivery or to the development of puerperal endometritis. On the f…

A patient on oestrogen replacement therapy after hysterectomy developed endometriosis and adenocarcinoma. The involvement of the urinary tract and theories on the pathogenesis of endometriosis and adenocarcinoma in relation to oestrogen rep…

It now is evident after over 25 years of experience with modern contraceptive techniques that the health benefits of using family planning in general and of oral contraceptives (OCs) in particular are substantial and outweigh any risks or c…

Gonadotrophin-releasing hormone (GnRH) plays a pivotal role in the regulation of the reproductive system. Chemically synthesised GnRH and analogues have found wide application in clinical medicine. Pulsatile administration of GnRH is used i…

The protocol for in vitro fertilisation (IVF) at Tygerberg Hospital is presented and the results are analysed. Indications for ovulation induction for IVF included the following: (a) irreversible tubal damage; (b) infertility due to immunol…

A 47-year-old multiparous woman presented with endometriosis, true urinary incontinence, and the mucosal and skin lesions of pyoderma gangrenosum. The subsequent investigations, treatment and course are discussed, as well as the possible ca…

Postmenopausal endometrial tuberculosis is an uncommon condition. Two patients with this disease, 1 of whom also presented with a pyometra, are described. They were the only 2 patients with this disease out of 21742 patients admitted to the…

A patient presented with a dark, painful and bleeding umbilicus, and was found to have endometriosis of the umbilicus. The details are presented, as well as a discussion of the aetiology, incidence, differential diagnosis and histological f…

Thirty-six women with endometriosis externa were treated with danazol (Ladogar; Winthrop Laboratories, Division of Sterling Drug (SA) (Pty) Ltd) for 6 months. In 15 cases treatment was combined with conservative surgery. Of these patients 3…

Endometriosis is a fascinating disease--it is common and occurs with increasing frequency. The aetiology remains obscure, but Sampson's theory of retrograde menstruation and implantation is still the most popular and widely accepted. Certai…

A case of postmenopausal endometriosis is presented. Symptoms started 14 years after total abdominal hysterectomy and bilateral salpingo-oöphorectomy for endometriosis following oestrogen administration. The disease had a protracted course …