Cureus

BACKGROUND: Infertility is a serious health issue, affecting approximately 15% of couples of reproductive age worldwide. Abnormal uterine findings have been found in 34%-62% of infertile women. METHODS AND MATERIALS: This was a retrospecti…

The female reproductive tract microbiome has emerged as a potential factor associated with reproductive health, infertility, and outcomes of assisted reproductive technologies (ARTs). Growing interest in host-microbiome interactions has hig…

Introduction Transvaginal USG is the first-line imaging modality for evaluating female pelvic pathologies because of its accessibility and cost-effectiveness. However, indeterminate findings and operator dependence may limit its diagnostic …

Chronic postoperative inguinal pain (CPIP) affects an estimated 4%-21% of patients following inguinal hernia repair, with rates varying by technique, follow-up duration, and pain definition, and requires a systematic, multidisciplinary eval…

The rupture of an ovarian endometrioma during pregnancy is a rare cause of acute abdominal pain, and its underlying risk factors are incompletely understood. We report a case of ovarian endometrioma rupture during pregnancy complicated by d…

Pregnancy in a complex Müllerian anomaly is an uncommon and potentially catastrophic obstetric condition. It often remains undiagnosed until the patient presents in an emergency setting. Presentation of a rudimentary horn pregnancy near ter…

Iatrogenic ureteric injury is an uncommon but serious complication of gynaecological surgery, with significant potential for renal impairment, fistula formation, prolonged hospitalisation, and medico-legal consequences. The ureter is at ris…

Serous borderline tumors (SBTs) typically arise from the ovary, and their development within a paratubal cyst is an uncommon occurrence. We report a 22-year-old nulliparous woman with chronic dysmenorrhea and an enlarging right adnexal cyst…

46,XY disorders of sex development (DSDs) are rare congenital conditions resulting from impaired gonadal differentiation and/or steroidogenesis. The NR5A1 gene encodes steroidogenic factor 1 (SF-1), a key regulator of gonadal development an…

Abnormalities in the synthesis or structure of globin chains are known as hemoglobinopathies, and they produce a wide range of clinical phenotypes. When both alleles of the same gene carry different hemoglobin variants, this results in comp…

Endometriosis and polycystic ovary syndrome (PCOS) are common, multifactorial gynecological disorders shaped by endocrine imbalance, immune dysfunction, metabolic disruption, genetic susceptibility, and environmental exposures. Despite thei…

Undifferentiated gastrointestinal tumors with SMARCA4 deficiency are a rare subset of malignancies that often present as advanced, rapidly progressive disease. SMARCA4 loss is identified by immunohistochemistry, and affected tumors demonstr…

Solitary rectal ulcer syndrome (SRUS) is a benign rectal disorder associated with abnormal defecation and mucosal prolapse. Its clinical and endoscopic features may mimic inflammatory bowel disease (IBD). We report the case of a 28-year-old…

Introduction Abnormal uterine bleeding (AUB) is one of the common complaints affecting women across different stages of life. Aim The aim of this study was to determine the AUB spectrum in our population and correlate it with the histopatho…

Spontaneous expulsion of uterine fibroids is an uncommon clinical event, most frequently described in the postpartum period or after uterine artery embolisation. Expulsion of a very large submucosal fibroid without surgical intervention is …

Ovarian endometrioma is associated with infertility, whereas its treatment may compromise ovarian reserve. This retrospective cohort evaluated factors associated with spontaneous pregnancy after laparoscopic treatment of ovarian endometriom…

Spontaneous rupture of an unscarred uterus is an exceptionally rare but life-threatening obstetric complication. Its diagnosis may be particularly challenging when clinical manifestations are atypical and classical risk factors are absent. …

Tumour lysis syndrome (TLS) is a potentially fatal oncological emergency characterised by rapid cellular breakdown resulting in hyperkalaemia, hyperphosphataemia, hyperuricaemia, and hypocalcaemia, with subsequent acute kidney injury, cardi…

Spontaneous rupture of the uterine artery during pregnancy is an exceptionally rare and life-threatening obstetric emergency. It often presents with sudden hemodynamic instability in the absence of external bleeding, posing diagnostic and m…

Ovarian carcinomas represent the second most common malignancy of the female genital tract; however, primary squamous cell carcinoma (SCC) is a rare subtype. Most of these tumors arise from malignant transformation of mature cystic teratoma…

Gynecological ultrasonography (USG) is integral to evaluating adnexal masses, adenomyosis, endometriosis, and other pelvic pathologies. Despite advances in imaging, substantial variability in terminology and reporting persists, potentially …

Steroid cell tumors of the ovary are rare, often hormonally active neoplasms that may present with features of hyperandrogenism. We report the case of a 60-year-old woman who initially presented with postmenopausal bleeding and a reassuring…

Background Ovarian cancer is a major cause of cancer-related mortality among women and remains a significant diagnostic and therapeutic challenge due to its heterogeneous nature, absence of effective screening strategies, and frequent prese…

Mature cystic teratomas (MCTs) can rarely undergo malignant transformation, most frequently into squamous cell carcinoma. Preoperative diagnosis remains challenging because of the complex internal architecture of dermoid cysts, which may ob…

OBJECTIVE: This study aims to assess the surgical outcomes and learning curve of robotic single-port vaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) for hysterectomy in benign gynecologic conditions. MATERIALS AND METH…