Cureus

Endometriosis is a chronic, estrogen-dependent disease affecting women of reproductive age. Although extragenital involvement is not uncommon, appendiceal endometriosis is a rare entity that may present with acute abdominal pain, often mimi…

An imperforate hymen (IH) is an uncommon congenital condition resulting from the failure of the synovaginal bulbus to canalize during embryonic development. While it typically presents with primary amenorrhea, cyclic pain, and hematocolpos,…

BACKGROUND: The prostaglandin E receptor 1 (PTGER1) is a G-protein-coupled receptor (GPCR) located on chromosome 9. It encodes prostaglandin E2 receptor 1 (EP1), a 42kDa prostaglandin receptor involved in mediating many physiological and pa…

Dialysis disequilibrium syndrome (DDS) is a rare but potentially fatal complication of renal replacement therapy, typically characterized by cerebral edema and often precipitated by the rapid correction of severe azotemia. Clinical symptoms…

Bacterial vaginosis (BV) is a prevalent vaginal infection in women of reproductive age, characterized by a dysbiosis of the vaginal microbiota. A healthy vaginal environment is typically dominated by Lactobacillus species, which maintain a …

Disseminated peritoneal leiomyomatosis (DPL) is a rare benign smooth muscle tumor that proliferates along the peritoneal surface and is mostly reported in young women. Our cases highlight the wide clinical and radiologic mimics of DPL, incl…

This case series highlights the use of dorsal root ganglion (DRG) stimulation for refractory chronic abdominal pain in three patients who failed to respond to conventional therapies. DRG stimulation modulates pain signals by targeting the s…

Endometriosis is a common condition among women where tissue resembling the uterine lining grows outside the uterus. This misplaced tissue can develop in several areas, including the peritoneum, pouch of Douglas, vagina, uterosacral ligamen…

Endometriosis is a gynecological condition that primarily affects women of reproductive age and is a leading cause of infertility. Ovarian endometriomas (OMAs) are cystic forms often seen in advanced stages of the disease. This report descr…

Background Acute pancreatitis is a common gastrointestinal emergency that ranges from mild, self-limiting inflammation to severe disease with multi-organ dysfunction and high mortality. Traditional prognostic scoring systems such as Bedside…

Background Infertility poses a substantial challenge in the realm of reproductive health, impacting numerous couples globally. Intrauterine abnormalities like polyps, submucosal fibroids, and uterine septa can impede the process of successf…

BACKGROUND: Menopause affects 1.5 million women annually, with perimenopause lasting 2-8 years and causing symptoms like hot flashes, sleep disturbances, mood changes, and joint pain. While hormone replacement therapy (HRT) is effective, sa…

Background Artificial insemination with donor sperm (AID) is an established treatment option for various indications. The outcome of such treatment is likely to be affected by different female factors and associated factors contributing to …

Background Nitrous oxide (N₂O) is commonly used during general anesthesia for ovum pickup during in vitro fertilization (IVF) cycles. N₂O deactivates methionine synthetase, thereby reducing the amount of thymidine available for DNA synthesi…

Background Adenomyosis refers to the presence of endometrial tissues within the uterine myometrium. The main presenting features are dyspareunia, dysmenorrhea, heavy menstrual bleeding (HMB), and chronic pelvic pain (CPP). With an increasin…

OBJECTIVE: This study was conducted to compare the efficacy and safety of Folisurge, a biosimilar recombinant follicle-stimulating hormone (r-FSH), with Gonal-f, an innovator r-FSH, in patients undergoing assisted reproductive technology (A…

BACKGROUND: Abnormal uterine bleeding (AUB) is a major gynecological complaint that significantly impacts women's quality of life, particularly during their reproductive years. Non-structural AUB presents a therapeutic challenge due to the …

Endometriosis is a chronic gynecological condition commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Owing to the limitations and adverse effects of traditional hormonal therapies, this study aimed to evaluat…

Lithium is a key treatment for bipolar disorder but is associated with significant endocrine and metabolic side effects, particularly lithium-induced hyperparathyroidism (LIH). Characterized by hypercalcemia and inappropriately normal or el…

Endocrine-disrupting chemicals (EDCs) are widespread environmental contaminants that interfere with hormonal regulation, affecting metabolism, reproduction, neurodevelopment, and overall health. This review presents an overview of recent ev…

OBJECTIVE: Determine the accuracy of deep endometriosis (DE) and ovarian endometrioma (OE) diagnosis on pelvic MRI in non-specialized tertiary healthcare, taking surgical diagnosis as the reference test. Additionally, we aimed to evaluate s…

Laparoscopic colposuspension with mesh is a common procedure performed to treat apical pelvic organ prolapse refractory to non-surgical interventions. Mesh complications involving a fistula are an uncommon event that typically occurs months…

Combined oral contraceptives (COCs) possess the ability to alter the normal composition of the gut microbiome and the permeability of the gastrointestinal (GI) tract, which may cause both gut-related and non-gut-related complications. The g…

BACKGROUND: Abnormal uterine bleeding (AUB) is a common gynecological condition affecting women of reproductive age and is associated with quality of life, physical well-being, and healthcare impact. AUB has varying etiologies classified as…

AIM: Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide. As patient education remains a critical tool in battling chronic conditions, including COPD, a potential role for artificial intelligence (AI) chat…