Frontiers in medicine

Front Med (Lausanne) · ISSN (print) 2296-858X · 408 papers in corpus
case-report 2025
doi:10.3389/fmed.2025.1537986 ·PMID:40303378

BACKGROUND: Endosalpingiosis, a rare benign condition characterized by ectopic fallopian tube-like epithelium, often coexists with endometriosis. This case report presents a unique instance of florid cystic endosalpingiosis confined to the …

observational 2025
doi:10.3389/fmed.2025.1650262 ·PMID:40978724

BACKGROUND: Cesarean scar pregnancy (CSP) is a high-risk ectopic pregnancy, and the influence of surgical treatments on subsequent fertility and pregnancy outcomes remains poorly understood. This study aimed to investigate the impact of dif…

other 2025
doi:10.3389/fmed.2025.1745761 ·PMID:41601801

This research aimed to determine the predictive value of a combined diagnosis of serum platelet endothelial cell adhesion molecule-1 (PECAM-1) and placental growth factor (PLGF) levels, gut microbiota count, and uterine artery Doppler ultra…

meta-analysis 2025
doi:10.3389/fmed.2025.1709969 ·PMID:41625758

BackgroundThe concept of "quality markers" (Q-markers) has emerged as a key solution to address limitations in the evaluation and standardization of traditional herbal medicines. Despite the introduction of various Q-marker identification s…

observational 2025
doi:10.3389/fmed.2025.1581059 ·PMID:40303371

INTRODUCTION: Dysmenorrhea symptoms are frequent and often self-treated using non-prescription medicines. METHODS: To further characterize women with dysmenorrhea using a combination of hyoscine butylbromide plus paracetamol (PLUS) for sel…

case-report 2025
doi:10.3389/fmed.2025.1563914 ·PMID:41164164

We present the case of a 39-year-old Chinese woman who presented with a palpable mass in her abdominal wall and pelvic cavity 9 years after undergoing laparoscopic myomectomy. Six abdominal wall fibroids, 18 intramural fibroids, 1 posterior…

observational 2025
doi:10.3389/fmed.2025.1555256 ·PMID:40357288

OBJECTIVE: This study aimed to evaluate the effects of transcervical resection of the septum (TCRS) on reproductive outcomes in women of reproductive age with two types of uterine septa. METHODS: In this retrospective cohort study, we eval…

meta-analysis 2025
doi:10.3389/fmed.2025.1554875 ·PMID:40438372

INTRODUCTION: Recurrent spontaneous abortion (RSA) represents a significant challenge in obstetrics and reproductive medicine. Causative factors in 40%-50% of RSA couples remain unknown, a condition termed unexplained recurrent spontaneous …

other 2025
doi:10.3389/fmed.2025.1563179 ·PMID:40950960

BACKGROUND: Phthalate esters (PAEs) are a class of synthetic compounds that are extensively utilized in a range of consumer products, and they significantly affect both environmental conditions and human reproductive health. Especially, man…

observational 2025
doi:10.3389/fmed.2025.1677721 ·PMID:41393133

OBJECTIVE: Robotic-assisted surgery is increasingly used in gynecology, offering technological and ergonomic benefits that overcome the limitations of traditional laparoscopy. This retrospective study evaluates perioperative outcomes, learn…

meta-analysis 2025
doi:10.3389/fmed.2025.1488866 ·PMID:40046932

OBJECTIVES: Adenomyosis (AM) is a chronic disorder that significantly impacts women's health and quality of life worldwide, particularly by causing progressive impairment in fertility. This study aimed to summarize and visualize the literat…

other 2025
doi:10.3389/fmed.2025.1693787 ·PMID:41384115

BACKGROUND: The comorbidity of rheumatoid arthritis (RA), a chronic autoimmune disease, with cervical cancer has garnered a lot of attention. Cervical cancer is much more common in RA patients than in the general population, which may be ca…

other 2025
doi:10.3389/fmed.2025.1733063 ·PMID:41601772

BACKGROUND: Ovarian endometriotic cysts (OEC) are classified into early (I-II) and advanced (III-IV) stages. Stage IV OEC is characterized by severe adhesions and anatomical distortion that complicate surgical management. Accurate preoperat…

other 2025
doi:10.3389/fmed.2025.1561512 ·PMID:40552179

OBJECTIVE: This study aims to observe whether right-sided stellate ganglion block (SGB) before surgery can improve early postoperative recovery quality in peri-menopausal women undergoing elective gynecological laparoscopic surgery. METHOD…

meta-analysis 2025
doi:10.3389/fmed.2025.1694281 ·PMID:41234925

UNLABELLED: Endometriosis is a chronic inflammatory disease characterized by pelvic pain and infertility, with oxidative stress playing a key role in its pathogenesis. Although antioxidant supplementation has been proposed as a potential ad…

rct 2025
doi:10.3389/fmed.2025.1626575 ·PMID:41030271

BACKGROUND: Endometriosis is a chronic gynecological condition that can result in pelvic pain and infertility, thereby significantly impacting women's reproductive health. Psychological disorders such as anxiety and depression are common in…

observational 2025
doi:10.3389/fmed.2025.1626519 ·PMID:40776914

BackgroundTuberculosis can negatively impact both overall health and female reproductive function. This study investigated the relationship between the interferon-gamma release assay (IGRA) status and pregnancy outcomes in infertile women, …

observational 2025
doi:10.3389/fmed.2025.1681770 ·PMID:41195173

BACKGROUND: To evaluate the association between seasonal temperature variations and clinical outcomes of in vitro fertilization (IVF), aiming to provide theoretical foundations for optimizing protocol timing in reproductive medicine. METHO…

observational 2025
doi:10.3389/fmed.2025.1574457 ·PMID:40606450

PURPOSE: Vaginal natural orifice transluminal endoscopic surgery (V-NOTES) has emerged as an innovative surgical approach that combines the advantages of endoscopic surgery with those of the vaginal approach. This article presents the initi…

observational 2025
doi:10.3389/fmed.2025.1533344 ·PMID:40417664

Endometrial cancer remains one of the most common malignancies in women, and its incidence is particularly increasing in developed countries. Despite the well-known promotive role of excessive exposure to estrogen, many other details of the…

review 2025
doi:10.3389/fmed.2025.1559224 ·PMID:40776920

Acanthamoeba keratitis (AK) is a rare corneal disease that can lead to permanent visual impairment. Its incidence is relatively low when compared with that of other forms of infectious keratitis. As early clinical diagnosis of AK is challen…

meta-analysis 2025
doi:10.3389/fmed.2025.1589193 ·PMID:41001383

BACKGROUND: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting reproductive-age women and is often associated with infertility challenges. Recent studies suggest that vitamin D levels play a significant role in reprod…

review 2025
doi:10.3389/fmed.2025.1662794 ·PMID:41140697

Reactive oxygen species (ROS) play dual roles in the pathophysiology of endometrial cancer (EC). Oxidative stress induced by ROS can promote the survival and proliferation of cancer cells, whereas excessive accumulation of ROS can lead to v…

nonrandomized-trial 2025
doi:10.3389/fmed.2025.1664433 ·PMID:41133152

Prior studies have revealed that electrical stimulation of the vagus nerve modifies platelet phenotype and reduces blood loss in preclinical models of soft tissue injury. This pilot trial (NCT06064851) sought to determine whether the use of…

meta-analysis 2025
doi:10.3389/fmed.2025.1552185 ·PMID:40166065

OBJECTIVE: This meta-analysis aimed to assess the diagnostic efficacy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for the detection of rectosigmoid deep infiltrating endometriosis (DIE). METHODS: A thorough system…