Asgi Fazleabas

Endometriosis, defined as the growth of endometrial-like tissues outside the uterus, is a common disease among women. Numerous in vivo rodent models of endometriosis have been developed to explore multiple aspects of this poorly understood …

The aetiology of endometriosis remains poorly understood. In vitro model systems provide the opportunity to identify the mechanisms driving disease pathogenesis using human cells. Three-dimensional models, particularly organoid systems, hav…

Pain is a debilitating symptom of endometriosis, and its mechanisms are often explored using rodent models. However, a lack of harmonization amongst models and behavioural measures, in addition to inconsistent reporting, might limit the ove…

Abstract Despite being a deadly disease, debates over the origins of ovarian cancer have persisted for many decades. There is evidence that some tumors may not originate from the ovary, but are the result of cells that have moved to the ova…

Baboon ( Papio anubis) models of endometriosis are thought to mimic the early stages of spontaneous human peritoneal endometriotic disease. The objective of this study was to investigate the presence and course of nerve fibre ingrowth durin…

Endometriosis is one of the most common gynecological disorders which are a cause of chronic pelvic pain and infertility. The molecular mechanisms associated with the pathophysiology of the endometriosis related infertility are poorly under…

Endometriosis was first described by Carl von Rokitansky in 1860, but to date, over 150 years later, endometriosis remains an enigmatic disease. Its pathophysiology, diagnosis and medical treatment continue to challenge basic and medical sc…