Xudong Chen

ORCID: 0000-0002-2989-5608 · 2 papers in corpus

lab-animal 2026

Curcumin Alleviates Endometriosis in Sexually Mature Female Mice by Targeting PKA and Inhibiting De Novo Estrogen Synthesis

Biomedicines ·doi:10.3390/biomedicines14092099

Background: Endometriosis is an estrogen-dependent disorder with limited treatment options. The precise molecular targets of curcumin and its effects on local estrogen synthesis in this disease remain unclear. Methods: We investigated curcu…

lab-animal 2012

The nuclear factor- B pathway is involved in matrix metalloproteinase-9 expression in RU486-induced endometrium breakdown in mice

·doi:10.1093/humrep/des110

background: Progesterone-withdrawal (WP)-induced endometrial breakdown occurs in both physiological and pathological processes such as menstruation and abortion. However, the underlying mechanisms are not clearly understood. As the nuclear …