Liu S

Minimally invasive thermal ablation therapies, including microwave ablation (MWA) and radiofrequency ablation (RFA), have emerged as effective alternatives to traditional surgical approaches for the management of symptomatic uterine fibroid…

Recent advancements in tissue clearing and three-dimensional (3D) visualization technologies have enabled subcellular-level examination of entire organs, particularly in complex structures such as the ovary and uterus. Traditional histologi…

The management of nasopharyngeal cancer (NPC) is rapidly evolving, with immune checkpoint inhibitors emerging as a prominent treatment approach. However, drug development targeting specific molecular and cellular abnormalities in NPC has sl…

BackgroundPolycystic ovary syndrome (PCOS) is widely acknowledged as the prevailing reproductive endocrine disorder accompanied by numerous metabolic dysfunctions. However, there has been a lack of systematic examination regarding the amino…

Introduction and hypothesisFemale bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome (IC/BPS). Numerous research indirectly prove that Female bladder pain syndrome (FBPS) is associated with immune-…

ObjectiveTo propose a prediction model aimed at increasing the live birth rate of patients undergoing two-cell embryo transfer while eliminating multiple pregnancy complications.MethodsWomen who underwent their first In Vitro Fertilization …

BackgroundSpontaneous abortion has been associated with higher risk of type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM), while the evidence remains equivocal. This study aimed to examine the association between sponta…

This study investigates the effects of astaxanthin on oxidative stress, mitochondrial function, and follicular development in mouse preantral follicles, with a focus on the involvement of the adenosine monophosphate-activated protein kinase…

IntroductionLow-grade endometrial stromal sarcoma (LGESS) is a rare malignant tumor of the uterus, characterized by slow growth. Early-stage LGESS is associated with favorable survival, but it has a high recurrence rate. The primary treatme…

INTRODUCTION: Endometriosis is a chronic gynecological disorder that significantly impacts women of reproductive age. Recent evidence suggests a bidirectional link between endometriosis and brain functional networks, though the causal mecha…

Songwei Feng,1,* Yuru Wang,1,* Sicong Liu,2,* Yueming Zhang,1 Leilei He1 1Department of Obstetrics and Gynaecology, The Fourth Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Department of Obstetrics and Gyna…

BACKGROUND: Endometriosis (EMS), a well-recognized chronic inflammatory disorder, characterized by significant immune dysregulation, in which myeloid-derived suppressor cells (MDSCs) are essential for facilitating immunosuppression and driv…

Curcumin, the principal bioactive compound derived from turmeric, possesses a wide range of therapeutic properties such as anti-inflammatory, antioxidant, and wound-healing properties. Recent studies suggest that curcumin may alleviate HMGB…

BACKGROUND: Mesenchymal stem cells (MSCs) isolated from umbilical cord blood (UCB) exhibit significant therapeutic efficacy in endometriosis; however, the molecular mechanisms governing their regulation remain incompletely elucidated. This …

ObjectiveA growing number of research papers have looked at the influence of exercise on pain severity in people with primary dysmenorrhea, but the findings have been inconsistent. The purpose of this research was to thoroughly evaluate the…

BackgroundAcute pancreatitis (AP) is a complex condition requiring immediate treatment. Both extracellular vesicles derived from human umbilical cord mesenchymal stem cells (hUC-MSC-EVs) and emodin, a naturally occurring anthraquinone used …

ObjectiveThis study aims to demonstrate that the EN2 protein in cervical mucus may serve as a novel biomarker for screening endometrial cancer.Materials and methodsThis study included 133 patients who were treated at Beijing Obstetrics and …

BackgroundHuman decidual mesenchymal stem cells (hDMSCs) play crucial roles in pregnancy. The decreased resistance of hDMSCs to oxidative stress is a key factor contributing to recurrent spontaneous abortion (RSA). miRNAs have essential fun…

BACKGROUND: Insomnia is increasingly emerging as a significant concern in public health, with a longstanding emphasis on its relationship with overall well-being. Nevertheless, few research has been devoted to investigating the relationship…

BackgroundThis retrospective cohort study aimed to evaluate the impact of insulin resistance (IR) on clinical outcomes in polycystic ovary syndrome (PCOS) patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection …

The human cytochrome P450 19A1 (CYP19A1, aromatase) is a heme-containing protein catalyzing the final steps of the biosynthesis of the steroid hormone 17β-estradiol. It is a key target for the treatment of sex-hormone-related disorders due …

BACKGROUND: Acute pancreatitis (AP) can be mild and self-limited, but it can also become severe acute pancreatitis (SAP) and lead to multi-organ dysfunction. It is still difficult to identify patients who may develop severe disease at an ea…

RationaleIntramural pregnancy is a rare form of ectopic pregnancy in which the gestational sac is embedded entirely within the myometrium, with no connection to the uterine cavity. Early diagnosis and timely management are challenging.Patie…

Background: Studies have found that post-traumatic growth exists in patients with recent hysterectomy. However, previous studies have overlooked heterogeneity within groups. There is a lack of research on whether there are different categor…

ObjectivePrimary dysmenorrhea (PD) is a recurrent disease. The current treatments for PD often fail to provide long-lasting effects, underscoring the necessity for new treatment options that can offer durable benefits. Previous studies have…