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OBJECTIVE: We investigated the effects of dienogest (DNG), which has a profile similar to that of natural progesterone (P4), on the favorable effects of estrogen in endothelial function. METHODS: (1) Human umbilical vein endothelial cells w…
A unicornate uterus with a rudimentary horn is a rare Müllerian duct abnormality. This uterine anomaly may cause variable gynecologic complications, including hematometra, endometriosis leading to acute pelvic pain, infertility, and obstetr…
OBJECTIVE: To determine the effects of oxidative stress on the quality of oocytes and embryos, 8-hydroxy-2'-deoxyguanosine (8-OHdG) in granulosa cells was quantitatively studied during an in vitro fertilization and embryo transfer (IVF-ET) …
Endometriosis is associated with marked subfertility and various causes for this subfertility have been previously studied. The poor quality of oocytes has been suggested as one possible cause. In this study, we evaluated the quality of ooc…
ObjectiveTo evaluate the efficacy of half-dose GnRH agonist therapy for endometriosis.DesignProspective, longitudinal pilot study.SettingOsaka University Hospital.Patient(s)Patients with symptomatic endometriosis.Intervention(s)Fifteen pati…