Santhamma B

No ORCID on file · 2 papers in corpus · active 2018-2019
2019
EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model.
Scientific reports ·doi:10.1038/s41598-019-53467-w

Uterine fibroids (UFs) are associated with irregular or excessive uterine bleeding, pelvic pain or pressure, or infertility. Ovarian steroid hormones support the growth and maintenance of UFs. Ulipristal acetate (UPA) a selective progestero…

2018
Esters of levonorgestrel and etonogestrel intended as single, subcutaneous-injection, long-lasting contraceptives.
Steroids ·doi:10.1016/j.steroids.2018.07.010

An effort with the goal of discovering single-dose, long-lasting (>6 months) injectable contraceptives began using levonorgestrel (LNG)-17-β esters linked to a sulfonamide function purposed as human carbonic anhydrase II (hCA 2) ligands. On…