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BACKGROUND: Endometriosis is a common gynecological disorder causing pelvic pain and infertility. While generally attributed to peritoneal implants of endometrium derived from retrograde menstruation, the contribution of cells from the circ…
OBJECTIVE: To determine if microRNAs that are altered in the circulation of women with endometriosis affect metabolic gene expression in hepatic cells. DESIGN: In vitro study. SUBJECTS: Deidentified tissue from women with endometriosis. …
Endometriosis is a gynecological inflammatory disorder characterized by the presence of endometrial tissue outside of the uterus. It affects 10-15% of reproductive aged women, causing pelvic pain and infertility. Existing treatments for end…
OBJECTIVE: To investigate the function of HOXA11-antisense long non-coding RNA (HOXA11-AS) in endometriosis treatment response. METHODS: Tissue samples (ectopic and eutopic endometrium) were obtained from surgically diagnosed subjects with…