Benjamin Tycko (237065)

No ORCID on file · 4 papers in corpus · active 2017

Study types

  • other 4

Condition tags

  • endometriosis 4
other 2017
Analysis of 5mC and 5hmC in endometriosis lesions and stroma cells.
·doi:10.1371/journal.pone.0170859.g003

A) Immunofluorescence analysis of the levels of expression of 5mC (green) and 5hmC (red) in tissue samples of women with endometriosis and controls, showing disease-dependent loss of 5hmC in the epithelial but not in the stromal cell compar…

other 2017
Gene-specific alterations in DNA methylation in primary ovarian endometriosis stromal cells (OESC) compared to control endometrial stromal cells (CESC), chromatin state enrichment analysis of DM genes in endometriosis, and bi-seq validation for DAPK1.
·doi:10.1371/journal.pone.0170859.g001

A) Heat maps of gene-specific methylation changes in endometriotic stroma cells vs. controls. Supervised hierarchical clustering of the 450K methylation BeadChip data analyzed at the CpG level (FDR q-values .15) and at the element-level (q-…

other 2017
Validation of RNA-sequencing by Q-PCR and effects of 5Aza-dC on a subset of DM and DE genes in CESC and OESC.
·doi:10.1371/journal.pone.0170859.g005

This figure shows average gene expression levels in CESC and OESC, from two or three biological replicates, after treatment with 5aza-dC for 72 hrs. All values were normalized to the mean of the non-treated CESC controls (0) set to 1. A) Th…

other 2017
WNT5A protein expression at the whole tissue level.
·doi:10.1371/journal.pone.0170859.g006

Immunostaining for the WNT5A protein was done on FFPE sections of endometriotic (n = 14) and normal endometrial tissue (n = 14) samples. Representative pictures from control endometrium and endometriotic lesions at proliferative and secreto…